{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/alpha-amylase-from-bacillus-megaterium-expressed-in-bacillus-subtilis",
  "slug": "alpha-amylase-from-bacillus-megaterium-expressed-in-bacillus-subtilis",
  "name": "alpha-Amylase from Bacillus megaterium expressed in Bacillus subtilis",
  "identifiers": {
    "e_number": null,
    "ins_number": "1100(iv)",
    "cas_number": null,
    "inchikey": null,
    "pubchem_cid": null
  },
  "functional_class": "Flour treatment agent",
  "summary": "This is an alpha-amylase whose gene comes from one bacterium and is expressed in another, a common arrangement in modern enzyme production. Codex lists it separately from the parent organisms.",
  "derivation_summary": "Produced by fermenting Bacillus subtilis carrying the amylase gene from Bacillus megaterium. The enzyme is purified away from the production organism.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": null,
          "effective_from": "1999",
          "citation": {
            "ref": "CXS 192-1995 Table Three, INS 1100(iv)",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        }
      ]
    }
  ],
  "names": [],
  "hazard_reference_values": [],
  "sources": [
    {
      "key": "gsfa",
      "name": "Codex General Standard for Food Additives (CXS 192-1995)",
      "publisher": "Codex Alimentarius Commission (FAO/WHO)",
      "licence": "FAO terms — non-commercial use with attribution",
      "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/",
      "retrieved_at": "2026-09-07T07:54:15.059Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"alpha-Amylase from Bacillus megaterium expressed in Bacillus subtilis\", https://foodadditiveindex.com/additives/alpha-amylase-from-bacillus-megaterium-expressed-in-bacillus-subtilis. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.401Z"
}