{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/cyclodextrin-gamma",
  "slug": "cyclodextrin-gamma",
  "name": "Cyclodextrin, gamma-",
  "identifiers": {
    "e_number": null,
    "ins_number": "458",
    "cas_number": null,
    "inchikey": "GDSRMADSINPKSL-HSEONFRVSA-N",
    "pubchem_cid": 5287407
  },
  "functional_class": "Thickener",
  "summary": "Gamma-cyclodextrin is the eight-unit ring, with the largest cavity of the three and the highest solubility. It is used to carry and stabilise flavours and fat-soluble vitamins.",
  "derivation_summary": "Produced enzymatically from starch, forming a closed ring of eight glucose units.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": null,
          "effective_from": "2001",
          "citation": {
            "ref": "CXS 192-1995 Table Three, INS 458",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        }
      ]
    }
  ],
  "names": [
    {
      "name": "17465-86-0",
      "type": "cas",
      "source": "pubchem"
    },
    {
      "name": ".gamma.-Cyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "ALFADEX IMPURITY B [EP IMPURITY]",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Betadex  EP Impurity B;Alfadex EP Impurity B",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Betadex EP Impurity B",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cavamax w8",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cyclodextrin, gamma-",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "cyclomalto-octaose",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cyclomaltooctaose",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cyclooctaamylose",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "CYCLOOCTAKIS-(1->4)-(.ALPHA.-D-GLUCOPYRANOSYL)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cyclooctapentylose",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Dexy Pearl gamma-100",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "g-cyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma cyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gamma Cyclodextrin, United States Pharmacopeia (USP) Reference Standard",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-CD",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, >=98%",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, powder, BioReagent, suitable for cell culture, >=98%",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, produced by Wacker Chemie AG, Burghausen, Germany, >=90.0% cyclodextrin basis (HPLC)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, produced by Wacker Chemie AG, Burghausen, Germany, >=98% (on dry basis)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, purum, >=98.0% (HPLC)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gamma-Dextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gammacyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gammacyclodextrin CRS",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gammadex [EP monograph]",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ins no.458",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ins-458",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "KZJ0BYZ5VA",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ringdex C",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Schardinger ?-Dextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Sugammadex Impurity 48",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "|A-?Cyclodextrin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "cyclooctakis-(1 inverted exclamation marku4)-(|A-D-glucopyranosyl) (cyclomaltooctaose or |A-cyclodextrin)",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "cyclooctakis-(1 inverted exclamation marku4)-(|A-D-glucopyranosyl) (cyclomaltooctaose or |A-cyclodextrin); Cyclomaltooctaose, Schardinger |A-Dextrin, gamma-Cyclodextrin, Cyclooctaamylose",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "gamma-Cyclodextrin, Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, 98.0-102.0% cyclodextrin basis",
      "type": "iupac",
      "source": "pubchem"
    }
  ],
  "hazard_reference_values": [],
  "sources": [
    {
      "key": "gsfa",
      "name": "Codex General Standard for Food Additives (CXS 192-1995)",
      "publisher": "Codex Alimentarius Commission (FAO/WHO)",
      "licence": "FAO terms — non-commercial use with attribution",
      "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/",
      "retrieved_at": "2026-09-07T07:54:15.059Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Cyclodextrin, gamma-\", https://foodadditiveindex.com/additives/cyclodextrin-gamma. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.496Z"
}