{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/glucono-delta-lactone",
  "slug": "glucono-delta-lactone",
  "name": "Glucono delta-lactone",
  "identifiers": {
    "e_number": null,
    "ins_number": "575",
    "cas_number": "90-80-2",
    "inchikey": "PHOQVHQSTUBQQK-SQOUGZDYSA-N",
    "pubchem_cid": 7027
  },
  "functional_class": "Acidity regulator",
  "summary": "Glucono-delta-lactone is an acid that releases slowly as it dissolves, which makes it the coagulant for silken tofu and the acidifier in cured sausages and some baking powders. The delay is the point of it.",
  "derivation_summary": "Produced by fermenting glucose to gluconic acid and then drying it into the lactone ring form, which reverts to the acid on contact with water.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 184.1318",
            "url": "https://www.ecfr.gov/current/title-21/section-184.1318"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "permitted_with_conditions",
      "status_label": "Permitted, with conditions",
      "provision_count": 5,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": null,
          "effective_from": "1999",
          "citation": {
            "ref": "CXS 192-1995 Table Three, INS 575",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        },
        {
          "status": "permitted_with_conditions",
          "food_category": {
            "system": "codex",
            "code": "01.2.1.2",
            "name": "Fermented milks (plain), heat-treated after fermentation"
          },
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": "GSFA notes: 631",
          "effective_from": "2024",
          "citation": {
            "ref": "CXS 192-1995 Table One, INS 575, food category 01.2.1.2",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        },
        {
          "status": "permitted_with_conditions",
          "food_category": {
            "system": "codex",
            "code": "01.6.6",
            "name": "Whey protein cheese"
          },
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": null,
          "effective_from": "2006",
          "citation": {
            "ref": "CXS 192-1995 Table One, INS 575, food category 01.6.6",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        },
        {
          "status": "permitted_with_conditions",
          "food_category": {
            "system": "codex",
            "code": "06.4.1",
            "name": "Fresh pastas and noodles and like products"
          },
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": null,
          "effective_from": "2013",
          "citation": {
            "ref": "CXS 192-1995 Table One, INS 575, food category 06.4.1",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        },
        {
          "status": "permitted_with_conditions",
          "food_category": {
            "system": "codex",
            "code": "13.2",
            "name": "Complementary foods for infants and young children"
          },
          "max_level": null,
          "max_level_unit": "GMP",
          "conditions": "GSFA notes: XS73",
          "effective_from": "2023",
          "citation": {
            "ref": "CXS 192-1995 Table One, INS 575, food category 13.2",
            "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/"
          },
          "source": "gsfa",
          "retrieved_at": "2026-09-07T07:54:15.059Z"
        }
      ]
    }
  ],
  "names": [
    {
      "name": "1335-57-5",
      "type": "cas",
      "source": "pubchem"
    },
    {
      "name": "4253-68-3",
      "type": "cas",
      "source": "pubchem"
    },
    {
      "name": "90-80-2",
      "type": "cas",
      "source": "ecfr"
    },
    {
      "name": "(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-one",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": ".delta.-D-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": ".delta.-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "1,5-D-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "1,5-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "beta-Glucono-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Canagliflozin Impurity H1",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "CAS-90-80-2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-(+)-Gluconic acid d-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-(+)-Gluconic acid delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-(+)-Gluconic acid |A-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "d-(+)-Glucono-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Aldonolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-delta-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "d-Gluconic acid .delta.-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic acid 1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "d-gluconic acid d-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic acid delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic acid lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic acid-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic acid-delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-Gluconic delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-glucono-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-glucono-delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D-threo-Aldono-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "delta gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "delta-Aldonolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "delta-D-Gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "delta-gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Deltagluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Fujiglucon",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Glucarolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Glucolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconate, lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic Acid Anhydride",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic Acid delta-Lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic acid lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic acid lactone (6CI)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic acid, delta-lactone, D-",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconic lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Glucono .delta.-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Glucono delta lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Glucono delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "glucono-1,5-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "glucono-delta-lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "gluconolactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Gluconolactone (USP)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "HSDB 488",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "INS NO.575",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "INS-575",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "LGC",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lysactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riken lactone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "WQ29KQ9POT",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "575",
      "type": "ins",
      "source": "gsfa"
    },
    {
      "name": "Glucono delta-lactone",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    },
    {
      "key": "gsfa",
      "name": "Codex General Standard for Food Additives (CXS 192-1995)",
      "publisher": "Codex Alimentarius Commission (FAO/WHO)",
      "licence": "FAO terms — non-commercial use with attribution",
      "url": "https://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/gsfa/en/",
      "retrieved_at": "2026-09-07T07:54:15.059Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Glucono delta-lactone\", https://foodadditiveindex.com/additives/glucono-delta-lactone. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.547Z"
}