{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/rennet-animal-derived-and-chymosin-preparation-fermentation-derived",
  "slug": "rennet-animal-derived-and-chymosin-preparation-fermentation-derived",
  "name": "Rennet (animal-derived) and chymosin preparation (fermentation-derived)",
  "identifiers": {
    "e_number": null,
    "ins_number": null,
    "cas_number": "9001-98-3",
    "inchikey": null,
    "pubchem_cid": null
  },
  "functional_class": null,
  "summary": "This listing covers both traditional animal rennet and the fermentation-produced chymosin that has largely replaced it. It is the enzyme that curdles milk into cheese, and the single most consequential dietary question in the whole dairy aisle.",
  "derivation_summary": "Animal rennet is extracted from the fourth stomach of unweaned calves. Fermentation-produced chymosin is the same enzyme made by yeast or fungi carrying the calf gene, and involves no animal. Both fall under one listing, so the entry alone does not tell you which was used — a cheese labelled with vegetarian rennet uses the fermentation form.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 184.1685",
            "url": "https://www.ecfr.gov/current/title-21/section-184.1685"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    }
  ],
  "names": [
    {
      "name": "9001-98-3",
      "type": "cas",
      "source": "ecfr"
    },
    {
      "name": "Rennet (animal-derived) and chymosin preparation (fermentation-derived)",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Rennet (animal-derived) and chymosin preparation (fermentation-derived)\", https://foodadditiveindex.com/additives/rennet-animal-derived-and-chymosin-preparation-fermentation-derived. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.670Z"
}