{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/riboflavin-5-phosphate-sodium",
  "slug": "riboflavin-5-phosphate-sodium",
  "name": "Riboflavin-5′-phosphate (sodium)",
  "identifiers": {
    "e_number": "E101",
    "ins_number": null,
    "cas_number": "130-40-5",
    "inchikey": "OHSHFZJLPYLRIP-BMZHGHOISA-M",
    "pubchem_cid": 23666409
  },
  "functional_class": null,
  "summary": "Riboflavin-5'-phosphate is a more water-soluble form of vitamin B2, used where the plain vitamin will not dissolve well enough — in drinks and liquid preparations, and as a yellow colour.",
  "derivation_summary": "Made by phosphorylating riboflavin, which is itself produced by fermentation or synthesis.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 184.1697",
            "url": "https://www.ecfr.gov/current/title-21/section-184.1697"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    }
  ],
  "names": [
    {
      "name": "130-40-5",
      "type": "cas",
      "source": "ecfr"
    },
    {
      "name": "22251-85-0",
      "type": "cas",
      "source": "pubchem"
    },
    {
      "name": "7,8-Dimethyl-10-ribitylisoalloxazine Phosphate Sodium",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E 101(ii)",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "FLAVIN MONONUCLEOTIDE MONOSODIUM SALT [MI]",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flavin Mononucleotide Sodium Salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "FMN-Na",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Infuvite (TN)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lactoflavin Phosphate Sodium Salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-(dihydrogen phosphate), monosodium salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-(dihydrogen phosphate), sodium salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-(sodium hydrogen phosphate)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-monophosphate sodium salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin 5'-phosphate sodium anhydrous",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "RIBOFLAVIN 5-PHOSPHATE SODIUM",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin monophosphate monosodium salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin phosphate (sodium) (Standard)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "RIBOFLAVIN PHOSPHATE SODIUM",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin Phosphate Sodium Salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin Phosphate Sodium Salt (~70%)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "riboflavin sodium phosphate",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin sodium phosphate (JP18)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "RIBOFLAVIN SODIUM PHOSPHATE ANHYDROUS",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin sodium phosphate CRS",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin Sodium phosphate(FMN-Na)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin sodium phosphate; riboflavin 5'-(sodium hydrogen phosphate)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin-5'-phosphate sodium",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "riboflavin-5'-phosphate sodium salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin-5-phosphate sodium",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavina 5 fosfato de sodio",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavine-5'-phosphate sodium",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavine-5?Phosphate Sodium",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Sodium Riboflavin Phosphate",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin B2 Phosphate Sodium Salt",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E101",
      "type": "e_number",
      "source": "openfoodtox"
    },
    {
      "name": "E106",
      "type": "e_number",
      "source": "pubchem"
    },
    {
      "name": "Sodium (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl hydrogen phosphate",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "Sodium 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-(hydroxyphosphinato)-D-ribitol",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "Sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate",
      "type": "iupac",
      "source": "openfoodtox"
    },
    {
      "name": "Riboflavin-5′-phosphate (sodium)",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [
    {
      "type": "ADI",
      "value": 0.5,
      "value_text": null,
      "unit": "mg/kg bw/day",
      "population": "consumers",
      "assessing_body": "EFSA ANS",
      "year": 2013,
      "opinion": {
        "ref": "doi:10.2903/j.efsa.2013.3357",
        "url": "https://doi.org/10.2903/j.efsa.2013.3357"
      }
    }
  ],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Riboflavin-5′-phosphate (sodium)\", https://foodadditiveindex.com/additives/riboflavin-5-phosphate-sodium. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.672Z"
}