{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/riboflavin",
  "slug": "riboflavin",
  "name": "Riboflavin",
  "identifiers": {
    "e_number": "E101",
    "ins_number": null,
    "cas_number": "83-88-5",
    "inchikey": "AUNGANRZJHBGPY-SCRDCRAPSA-N",
    "pubchem_cid": 493570
  },
  "functional_class": null,
  "summary": "Riboflavin is vitamin B2, a yellow-orange compound used both as a nutrient and as a colour. It appears in dairy products, desserts, cereals and drinks, and is what makes some vitamin preparations bright yellow.",
  "derivation_summary": "Produced commercially by fermentation with bacteria or fungi, and formerly by chemical synthesis. It also occurs naturally in milk, eggs and liver, but the additive is not extracted from those.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 2,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 184.1695",
            "url": "https://www.ecfr.gov/current/title-21/section-184.1695"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        },
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 73.450",
            "url": "https://www.ecfr.gov/current/title-21/section-73.450"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    }
  ],
  "names": [
    {
      "name": "83-88-5",
      "type": "cas",
      "source": "ecfr"
    },
    {
      "name": "(-)-riboflavin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "2vxa",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "6,7-Dimethyl-9-D-ribitylisoalloxazine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "7,8-Dimethyl-10-ribitylisoalloxazine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aqua-Flave",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Beflavin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Beflavine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Bisulase",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "C.I. Food Yellow 15",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Dermadram",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E 101(i)",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "E-101(iii)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Fiboflavin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flavaxin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flavin BB",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flaxain",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Freeda",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "HYRE",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "INS NO. 101(I)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ins no.101(iii)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ins-101(iii)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Isoalloxazine, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Isoalloxazine, 7,8-dimethyl-10-D-ribityl-",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lacto-flavin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lactobene",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lactoflavin",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Lactoflavine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "PureVita Vitamin B2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ribipca",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ribocrisina",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboderm",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Riboflavin (Vitamin B2)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavina",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavinequinone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Riboflavinum",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ribosyn",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ribotone",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ribovel",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Russupteridine Yellow III",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitaflavine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin B 2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin B-2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin B2",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Vitamin b2 (as riboflavin)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin Bi",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin G",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "vitamin-b2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "vitaminum b2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitasan B2",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E101",
      "type": "e_number",
      "source": "openfoodtox"
    },
    {
      "name": "1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "7,8-dimethyl-10-((2R,3R,4S)-2,3,4,5-tetrahydroxypentyl)benzo(g)pteridine-2,4-dione",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "7,8-dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)benzo(g)pteridine-2,4(3H,10H)-dione",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione",
      "type": "iupac",
      "source": "openfoodtox"
    },
    {
      "name": "Benzo(g)pteridine-2,4(3H,10H)-dione, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "Riboflavin",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [
    {
      "type": "ADI",
      "value": 0.5,
      "value_text": null,
      "unit": "mg/kg bw/day",
      "population": "consumers",
      "assessing_body": "EFSA ANS",
      "year": 2013,
      "opinion": {
        "ref": "doi:10.2903/j.efsa.2013.3357",
        "url": "https://doi.org/10.2903/j.efsa.2013.3357"
      }
    }
  ],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Riboflavin\", https://foodadditiveindex.com/additives/riboflavin. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.670Z"
}