{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/urea",
  "slug": "urea",
  "name": "Urea",
  "identifiers": {
    "e_number": "E927b",
    "ins_number": null,
    "cas_number": "57-13-6",
    "inchikey": "XSQUKJJJFZCRTK-UHFFFAOYSA-N",
    "pubchem_cid": 1176
  },
  "functional_class": null,
  "summary": "Urea is a yeast nutrient and fermentation aid, used chiefly in winemaking and baking to supply nitrogen to the yeast.",
  "derivation_summary": "Produced industrially from ammonia and carbon dioxide. Its 1828 laboratory synthesis was the first time an organic compound was made from inorganic material, which ended the idea that living things ran on a separate chemistry.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted",
      "status_label": "Permitted",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 184.1923",
            "url": "https://www.ecfr.gov/current/title-21/section-184.1923"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    }
  ],
  "names": [
    {
      "name": "57-13-6",
      "type": "cas",
      "source": "ecfr"
    },
    {
      "name": "20% Urea Cream",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Alphadrate",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Antisepsis bolus",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aqua Care",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aqua Care HP",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aquadrate",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Azodicarboxylic acid-diamide",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Balneum plus",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Carbaderm",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Carbamide",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Carbamide resin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Carbonyl diamide",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Carbonyldiamide",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Carbonyldiamine",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Caswell No. 902",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cem-urea",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Clear 40",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cracked Skin Cream",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E 927b",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Elaqua xx",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "EPA Pesticide Chemical Code 085702",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flexifoot",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Flexitol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Harnstoff",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Hydromol intensive",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "INS NO.927A",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "INS-927A",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Keratinamin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Lanaphilic",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Mocovina",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Nutraplus",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Pastaron",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Prespersion, 75 urea",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Protexa",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "RYNODERM",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Sential e",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "St.james balm",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Sterile Urea",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Supercel 3000",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ultra Mide",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Umecta Mousse",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Umecta Mousse Urea",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Urea 39% Cream",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea 40 Nail Gel",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea 40 Percent",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea Cream 40%",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea Cream 41%",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urea Foam",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ureacin-10 lotion",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ureacin-40 Creme",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ureaphil",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ureophil",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urepearl",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Urevert",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "UterCleanse",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vanamide",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Varioform ii",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Xurea",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "E927b",
      "type": "e_number",
      "source": "openfoodtox"
    },
    {
      "name": "Urea",
      "type": "iupac",
      "source": "openfoodtox"
    },
    {
      "name": "Urea",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [
    {
      "type": "ADI",
      "value": null,
      "value_text": "1",
      "unit": null,
      "population": null,
      "assessing_body": "EFSA",
      "year": null,
      "opinion": null
    }
  ],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Urea\", https://foodadditiveindex.com/additives/urea. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.762Z"
}