{
  "$schema": "https://foodadditiveindex.com/api/v1/schema.json",
  "id": "https://foodadditiveindex.com/additives/vitamin-d3",
  "slug": "vitamin-d3",
  "name": "Vitamin D3",
  "identifiers": {
    "e_number": null,
    "ins_number": null,
    "cas_number": "67-97-0",
    "inchikey": "QYSXJUFSXHHAJI-YRZJJWOYSA-N",
    "pubchem_cid": 5280795
  },
  "functional_class": null,
  "summary": "Vitamin D3, or cholecalciferol, is the form of vitamin D that human skin makes in sunlight and the form used in most fortification and supplements. Commercially it is almost always made from lanolin, the wax in sheep's wool, so it is not vegan unless specifically declared lichen-derived.",
  "derivation_summary": "Made by ultraviolet irradiation of cholesterol extracted from lanolin, sheared from living sheep. A vegan D3 from lichen exists but is more expensive and is normally advertised as such. D2, from yeast or fungi, is the plant-source alternative.",
  "regulatory_status": [
    {
      "jurisdiction": "US",
      "jurisdiction_name": "United States",
      "authority": "Food and Drug Administration",
      "status": "permitted_with_conditions",
      "status_label": "Permitted, with conditions",
      "provision_count": 1,
      "provisions": [
        {
          "status": "permitted_with_conditions",
          "food_category": null,
          "max_level": null,
          "max_level_unit": null,
          "conditions": null,
          "effective_from": null,
          "citation": {
            "ref": "21 CFR 172.380",
            "url": "https://www.ecfr.gov/current/title-21/section-172.380"
          },
          "source": "ecfr",
          "retrieved_at": "2026-09-07T18:25:51.549Z"
        }
      ]
    },
    {
      "jurisdiction": "CODEX",
      "jurisdiction_name": "Codex Alimentarius",
      "authority": "Codex Alimentarius Commission / JECFA",
      "status": "not_listed",
      "status_label": "Not listed",
      "note": "Does not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.",
      "provision_count": 0,
      "provisions": []
    }
  ],
  "names": [
    {
      "name": "67-97-0",
      "type": "cas",
      "source": "openfoodtox"
    },
    {
      "name": "(+)-Vitamin D3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "9,10-Secocholesta-5,7,10(19)-trien-3-ol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aciferol d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "AK R215 COMPONENT COLECALCIFEROL",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "AK-R215 COMPONENT COLECALCIFEROL",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Arachitol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Aviticol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Calceos",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Calci-d",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Calcichew d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Calciol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Caldrink d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Calfovit d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "CHOCAL",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "cholecalciferol",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "cholecalciferol (Vitamin D3)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cholecalciferol, D3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Cholecalciferolum",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Colecalciferol",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Colecalciferolo",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Colecalciferolum",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Colecalcipherol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D3-Vicotrat",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "D3-Vigantol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Dekristol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Delsterol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Delta-D",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Deparal",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Desunin",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Duphafral D3 1000",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ebivit",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Kora liquid",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "NEO Dohyfral D3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Oleovitamin D3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Osteocaps d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Plenachol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Provitina",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Rampage",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Ricketon",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Thorens",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Trivitan",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vi-de-3-hydrosol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vigantol",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "VIGANTOLETTEN",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vigorsan",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin d (cholecalciferol)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin D 3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin d assay system suitability",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "vitamin d-3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitamin D3",
      "type": "common",
      "source": "openfoodtox"
    },
    {
      "name": "Vitamin d3 (as cholecalciferol)",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "vitaminum d3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Vitinc Dan-Dee-3",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "Zymad",
      "type": "common",
      "source": "pubchem"
    },
    {
      "name": "(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol",
      "type": "iupac",
      "source": "openfoodtox"
    },
    {
      "name": "(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol",
      "type": "iupac",
      "source": "pubchem"
    },
    {
      "name": "Vitamin D3",
      "type": "label",
      "source": "ecfr"
    }
  ],
  "hazard_reference_values": [],
  "sources": [
    {
      "key": "ecfr",
      "name": "Electronic Code of Federal Regulations, Title 21",
      "publisher": "U.S. Government Publishing Office / National Archives",
      "licence": "Public domain",
      "url": "https://www.ecfr.gov/api/versioner/v1/full/2026-08-31/title-21.xml",
      "retrieved_at": "2026-09-07T18:25:51.549Z"
    }
  ],
  "citation_policy": "Cite as: Food Additive Index, \"Vitamin D3\", https://foodadditiveindex.com/additives/vitamin-d3. This site reports regulatory status and does not rate additives.",
  "generated_at": "2026-09-08T00:09:38.772Z"
}