Biotin

CAS 58-85-5

Biotin is vitamin B7, added to infant formula, drinks and fortified foods.

Where it is and isn’t permitted

Status of Biotin by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationPermitted21 CFR 182.8159retrieved 2026-09-07
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

What it is made from

Produced by chemical synthesis, and increasingly by fermentation.

  • Vegan
  • Vegetarian
CAS registry number
58-85-5
InChIKey
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
PubChem
CID 171548

Every name it appears under

62 recorded names. A label may use any of them.

CAS registry number

  • 58-85-5

As it appears in regulation

  • Biotin

Other names

  • (+)-Biotin
  • (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid
  • (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-valeric acid
  • 1H-thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)-
  • 2'-Keto-3,4-imidazolido-2-tetrahydrothiophene-N-valeric acid
  • 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid
  • 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid
  • Amerix Biotin
  • Beard
  • Bioepiderm
  • Bios II
  • BIOT
  • biotin
  • Biotin 100
  • Biotin Drops
  • Biotin Hair
  • Biotin ratiopharm
  • Biotina
  • Biotine
  • Biotinum
  • Biotitum
  • Biotn
  • Biotn Topical Serum
  • Bonogen Activator
  • Casotr Oil
  • cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid
  • cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid
  • cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid
  • coenzyme R
  • D(+)-Biotin
  • D-(+)-Biotin
  • d-biotin
  • DRUGGIST Bar
  • Factor S
  • Factor S (vitamin)
  • Gelfert, Biotin
  • Hair
  • Hair Cream
  • Hair Strengthens
  • Hairq-plus
  • Hermes, Biotin
  • Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid
  • Hiar Growth
  • Injacom H
  • Ritatin
  • Roche, Biotine
  • Roemary mint
  • Spai-sons Procapell
  • Spai-sons Prolac-vit
  • SUBIR
  • SUBIR EYELASH
  • Tk-nax
  • TWINKLE ESSENCE
  • Vitamin B-7
  • Vitamin B7
  • Vitamin Bw
  • Vitamin Essentaial
  • vitamin H

Systematic names

  • 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4beta,6aalpha))-
  • 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • ecfr retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/biotin.json