Calcium di-L-glutamate

INS 623

Used as a flavour enhancer.

Calcium diglutamate is a flavour enhancer used in reduced-sodium products.

Where it is and isn’t permitted

Status of Calcium di-L-glutamate by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationNot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.
Codex AlimentariusCodex Alimentarius Commission / JECFAPermitted, with conditions

1 food category

no numerical limit (good manufacturing practice)

CXS 192-1995 Table Three, INS 623and 1 further provisionretrieved 2026-09-07

What it is made from

Made by neutralising fermentation-derived glutamic acid with a calcium base.

  • Vegan
  • Vegetarian
InChIKey
UMVAYAXXQSFULN-QHTZZOMLSA-L
PubChem
CID 56841881

Every name it appears under

12 recorded names. A label may use any of them.

INS number

  • 623

CAS registry number

  • 5996-22-5

Other names

  • 9FA5OTO85L
  • calcium (S)-2-amino-4-carboxybutanoate
  • Calcium bis[(2S)-2-amino-4-carboxybutanoate]
  • Calcium di-L-glutamate
  • CALCIUM DI-L-GLUTAMATE CALCIUM DI-L-GLUTAMATE
  • Calcium diglutamate
  • Calcium L-glutamate (1:2)
  • calcium;(2S)-2-amino-5-hydroxy-5-oxopentanoate
  • Glutamic acid, calcium salt (2:1), L-
  • L-Glutamic acid, calcium salt (2:1)

Hazard reference values

Values set by assessing bodies. A body that has not set a value is not listed here.
TypeValuePopulationAssessed byOpinion
ADI30 mg/kg bw/dayconsumersEFSAnot identified in the dataset

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • gsfa retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/calcium-di-l-glutamate.json