Calcium lactobionate
110638-68-1 · 5001-51-4 · 4-O-?-D-Galactopyranosyl-D- gluconic acid calcium · 4-O-|?-D-Galactopyranosyl-D-gluconic acid monohydrate hemicalcium salt · 7D8YVA497F · alcium lactobionate · C24H42CaO24 · Calcium 4-O-beta-D-galactopyranosyl-D-gluconate (1:2) · Calcium 4-O-beta-D-galactopyranosyl-D-gluconate--water (1/2/2) · Calcium 4-O-hexopyranosylhexonate--water (1/2/2) · CALCIUM BIS(4-O-(.BETA.-D-GALACTOSYL)-D-GLUCONATE) · Calcium bis(4-O-(beta-D-galactosyl)-D-gluconate) · Calcium galactogluconate · Calcium lactobionate · CALCIUM LACTOBIONATE (1:2), DIHYDRATE. · CALCIUM LACTOBIONATE (MART.) · CALCIUM LACTOBIONATE (USP MONOGRAPH) · Calcium lactobionate (USP) · CALCIUM LACTOBIONATE (USP-RS) · Calcium lactobionate anhydrous · Calcium lactobionate dihydrate · Calcium lactobionate hydrate · Calcium lactobionate monohydrate · calciumlactobionate · Calciumlactobionatedihydrate · D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl-, calcium salt (2:1) · D-GLUCONIC ACID, 4-O-.BETA.-D-GALACTOPYRANOSYL-, CALCIUM SALT (2:1), DIHYDRATE · D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, calcium salt (2:1) · D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, calcium salt (2:1), dihydrate · Lactobionic acid calcium salt · Lactobionic Acid Calcium Salt Hydrate · Lactobionic acid, calcium salt (2:1) · Lactobionic acid, calcium salt (2:1), dihydrate · RHEMCSSAABKPLI-SQCCMBKESA-L · calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate · calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate;dihydrate · Calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate;hydrate · calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoate · Calcium lactobionateCAS 5001-51-4
Listed as a firming agent by the US.
Listed as firming agents (US)
- United States: Firming agent — FDA, Substances Added to Food: CALCIUM LACTOBIONATE
Calcium lactobionate is a firming agent used in dry pudding mixes.
Where it is and isn’t permitted
| Jurisdiction | Status | Scope and limits | Citation |
|---|---|---|---|
| Australia and New Zealand | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Canada | No listing matchedHealth Canada’s lists name additives without E or INS numbers, so this site matches them by exact name. A substance listed there under a name this site does not recognise has no row here. | ||
| European Union | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Great Britain | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Japan | No listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance. | ||
| South Korea | No listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance. | ||
| United States | Permitted, with conditions | 21 CFR 172.720retrieved 2026-10-17 | |
| Codex Alimentarius | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. |
How much is permitted
A listing usually limits the quantity as well as the food. Only one of the forms that takes is a figure: quantum satis and good manufacturing practice permit the amount the technological effect requires and no more, which is a limit rather than the absence of one. Figures below are the range across every food category this page is listed in, and categories differ between regulators — see how much is permitted.
| United States | — | 1 no quantity stated |
|---|
No regulator sets a figure for Calcium lactobionate. That is not an absence of control: where the listing says quantum satis or good manufacturing practice, the quantity is limited to what the effect requires.
What it is made from
Made by oxidising lactose to lactobionic acid and neutralising with calcium. The starting lactose is from milk.
- Not vegan
- Vegetarian
- May raise a kosher question
Compare other additives on the dietary indexes.
Allergen labelling
- From milk. Made by oxidising lactose, which Annex II item 7 names among milk products; the only lactose derivative it excepts is lactitol.
The EU’s list of allergens an ingredients list must emphasise is Regulation (EU) No 1169/2011, Annex II (consolidated text of 1 April 2025). Whether a product must declare one depends on what its additive was actually made from, which the label may not show; see the allergen origin index.
- CAS registry number
- 5001-51-4
- InChIKey
- FALNADDKNDADFQ-WNSOHMSISA-L
- PubChem
- CID 11954336
Every name it appears under
39 recorded names. A label may use any of them.
CAS registry number
- 110638-68-1
- 5001-51-4
As it appears in regulation
- Calcium lactobionate
Other names
- 4-O-?-D-Galactopyranosyl-D- gluconic acid calcium
- 4-O-|?-D-Galactopyranosyl-D-gluconic acid monohydrate hemicalcium salt
- 7D8YVA497F
- alcium lactobionate
- C24H42CaO24
- Calcium 4-O-beta-D-galactopyranosyl-D-gluconate (1:2)
- Calcium 4-O-beta-D-galactopyranosyl-D-gluconate--water (1/2/2)
- Calcium 4-O-hexopyranosylhexonate--water (1/2/2)
- CALCIUM BIS(4-O-(.BETA.-D-GALACTOSYL)-D-GLUCONATE)
- Calcium bis(4-O-(beta-D-galactosyl)-D-gluconate)
- Calcium galactogluconate
- Calcium lactobionate
- CALCIUM LACTOBIONATE (1:2), DIHYDRATE.
- CALCIUM LACTOBIONATE (MART.)
- CALCIUM LACTOBIONATE (USP MONOGRAPH)
- Calcium lactobionate (USP)
- CALCIUM LACTOBIONATE (USP-RS)
- Calcium lactobionate anhydrous
- Calcium lactobionate dihydrate
- Calcium lactobionate hydrate
- Calcium lactobionate monohydrate
- calciumlactobionate
- Calciumlactobionatedihydrate
- D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl-, calcium salt (2:1)
- D-GLUCONIC ACID, 4-O-.BETA.-D-GALACTOPYRANOSYL-, CALCIUM SALT (2:1), DIHYDRATE
- D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, calcium salt (2:1)
- D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, calcium salt (2:1), dihydrate
- Lactobionic acid calcium salt
- Lactobionic Acid Calcium Salt Hydrate
- Lactobionic acid, calcium salt (2:1)
- Lactobionic acid, calcium salt (2:1), dihydrate
- RHEMCSSAABKPLI-SQCCMBKESA-L
Systematic names
- calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate
- calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate;dihydrate
- Calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate;hydrate
- calcium;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoate
Hazard reference values
No reference value for this substance in the sources we hold.
Evidence and how bodies read it
Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.
Common questions
Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.
- What is Calcium lactobionate?
- Calcium lactobionate is a firming agent used in dry pudding mixes.
- What is Calcium lactobionate used for in food?
- It is listed as a firming agent — the role the US assigns it. This page shows every function each regulator records, with the citation for each.
- Is Calcium lactobionate banned in Europe?
- No. Calcium lactobionate does not appear on the EU's list of authorised food additives, which is not the same as being banned: the EU permits an additive only where it has authorised it, and usually the reason for an absence is that no one applied. The EU has made no finding against this substance. It does mean it may not be used as a food additive in the EU today.
- Where is Calcium lactobionate permitted?
- Of the seven regulators this site reads, the US permits it. Each permission is for named foods at named levels, not a blanket one; the table on this page gives them with citations.
- Is Calcium lactobionate vegan?
- No. Calcium lactobionate is animal-derived, though it is generally accepted as vegetarian. This page says what it is made from.
Sources for this page
- ecfr retrieved 2026-10-17
Full licence terms and publisher details on Sources. How this page is built and updated: Method.
Machine-readable: a JSON record of this additive is given on request —how to ask for access.
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