Calcium propionate
4075-81-4 · Bioban-C · C6H10CaO4 · Ca-PROPIONATE · calcium dipropanoate · Calcium dipropionate · Calcium propanoate · Calcium propionate · CALCIUM PROPIONATE (E 282) · Calcium propionate;Bioban-C; Calcium dipropionate · calciumpropionate · CalClum propionate · Caswell No. 151 · E 282 · EPA Pesticide Chemical Code 077701 · HSDB 907 · INS NO.282 · INS-282 · Propanoate (calcium) · Propanoic acid, calcium salt · Propanoic acid, calcium salt (2:1) · propionic acid calcium · Propionic acid calcium 1000 microg/mL in Acetonitrile:Water · Propionic acid, calcium salt · E282 · 282 · Calcium propanoate · Calcium propionate · Calcium propionate · Calciumpropionaat · Calciumpropionat · Kalcija propionāts · Kalcijev propionat · Kalcio propionatas · Kalcium-propionát · Kalciumpropionat · Kalsiumpropionaatti · Kaltsiumpropionaat · Propionan vápenatý · Propionat de calciu · Propionate de calcium · Propionato cálcico · Propionato de cálcio · Propionato di calcio · Propionian wapnia · Propjonat tal-kalċju · Προπιονικό ασβέστιο · Калциев пропионатE number E282INS 282CAS 4075-81-4
Listed as a preservative by Canada, Codex and the US.
Listed as preservatives (CA, US, Codex) · antioxidants (US)
- Canada: Preservative — Health Canada, List of Permitted Preservatives (List 11)
- United States: Antimicrobial agent — FDA, Substances Added to Food: CALCIUM PROPIONATE
- United States: Antimicrobial agents — 21 CFR 184.1221, citing 21 CFR 170.3(o)(2)
- Codex Alimentarius: Preservative — CXS 192-1995 Table One, INS 282
- United States: Antioxidant — FDA, Substances Added to Food: CALCIUM PROPIONATE

Calcium propionate is a mould inhibitor widely used in bread and other yeast-raised baked goods.
Where it is and isn’t permitted
| Jurisdiction | Status | Scope and limits | Citation |
|---|---|---|---|
| Australia and New Zealand | Permitted, with conditions | 10 food categories highest permitted level 4,000 mg/kg Show every food category
| Food Standards Code, Schedule 15, S15—5and 9 further provisionsretrieved 2026-10-17 |
| Canada | Permitted, with conditions | highest permitted level 4,000 mg/kg 4 permitted uses Show every permitted use
| Health Canada, List of Permitted Preservatives (List 11)and 3 further provisionsretrieved 2026-10-17 |
| European Union | Permitted, with conditions | 6 food categories highest permitted level 3,000 mg/kg Show every food category
| Regulation (EC) No 1333/2008, Annex IIand 5 further provisionsretrieved 2026-10-18 |
| Great Britain | Permitted, with conditions | 6 food categories highest permitted level 2,000 mg/kg or mg/l Show every food category
| Assimilated Regulation (EC) No 1333/2008, Annex II (as at 28 June 2024)and 5 further provisionsretrieved 2026-10-18 |
| Japan | Permitted, with conditions | Designated additive: Appended Table 1, item 372, プロピオン酸カルシウム (“Calcium Propionate” in the unofficial English translation). …Designated additive: Appended Table 1, item 372, プロピオン酸カルシウム (“Calcium Propionate” in the unofficial English translation). Standards for use — Specifications and Standards for Foods, Food Additives, etc. (MHW Notification No. 370 of 1959), Part II (Food Additives), F (Standards for use), entry プロピオン酸カルシウム: (1) [may be used only in the foods stated] “プロピオン酸カルシウムは、チーズ、パン及び洋菓子以外の食品に使用してはならない。” (2) [sets maximum levels of use for the foods stated] “プロピオン酸カルシウムの使用量は、プロピオン酸として、チーズにあってはその1kgにつき3.0g(ソルビン酸、ソルビン酸カリウム又はソルビン酸カルシウムを併用する場合には、プロピオン酸としての使用量及びソルビン酸としての使用量の合計量が3.0g)以下、パン及び洋菓子にあってはその1kgにつき2.5g以下でなければならない。” The Japanese is the standard as published. There is no official English translation of the Notification; the English in square brackets is this site’s description of what each sentence does, not a translation of the foods or the levels. Compositional specifications for this additive, in the same Notification, are not imported and are not shown here; nor are the general rules in F 添加物一般, which apply to every additive. | Regulations for Enforcement of the Food Sanitation Act (MHW Ordinance No. 23 of 1948), Appended Table 1retrieved 2026-10-18 |
| South Korea | Permitted, with conditions | Designated food additive: Standards and Specifications for Food Additives, Part III, 1. …Designated food additive: Standards and Specifications for Food Additives, Part III, 1. 일반식품첨가물 (general food additives), 프로피온산칼슘 (“Calcium Propionate”, the English the Code prints beside it). Main use (주용도) of 프로피온산칼슘: 보존료. Standard for use (사용기준) of 프로피온산칼슘: (1) [may be used only in the foods listed; sets a limit on the amount used] “프로피온산칼슘은 아래의 식품에 한하여 사용하여야 한다. 프로피온산칼슘의 사용량은 프로피온산으로서 1. 빵류 : 2.5g/kg 이하 2. 치즈류:3.0g/kg 이하(소브산, 소브산칼륨 또는 소브산칼슘과 병용할 때에는 프로피온산으로서 사용량과 소브산으로서 사용량의 합계가 3.0g/kg 이하) 3. 잼류:1.0g/kg 이하(소브산, 소브산칼륨, 소브산칼슘, 안식향산, 안식향산칼륨, 안식향산칼슘, 안식향산나트륨, 파라옥시안식향산메틸 또는 파라옥시안식향산에틸과 병용할 때에는 프로피온산으로서 사용량, 소브산으로서 사용량, 안식향산으로서 사용량 및 파라옥시안식향산으로서 사용량의 합계가 1.0g/kg 이하)” The Korean is the standard as published. There is no official English translation of the current Code (the English version on MFDS’s website is the 2020 edition and has no legal effect); the English in square brackets is this site’s description of what each sentence does, not a translation of the foods or the levels. Compositional specifications (Part IV) are not imported, nor are the general standards in Part II, which apply to every additive. | Standards and Specifications for Food Additives (식품첨가물의 기준 및 규격), MFDS Notification, Part III (Standards for use, by item)retrieved 2026-10-18 |
| United States | Permitted | 21 CFR 184.1221retrieved 2026-10-17 | |
| Codex Alimentarius | Permitted, with conditions | 2 food categories highest permitted level 3,000 mg/kg Show every food category and its notes
| CXS 192-1995 Table Three, INS 282and 2 further provisionsretrieved 2026-09-07 |
How much is permitted
A listing usually limits the quantity as well as the food. Only one of the forms that takes is a figure: quantum satis and good manufacturing practice permit the amount the technological effect requires and no more, which is a limit rather than the absence of one. Figures below are the range across every food category this page is listed in, and categories differ between regulators — see how much is permitted.
| Australia and New Zealand | 400 mg/kg – 4,000 mg/kg | 3 numeric limit, 7 GMP |
|---|---|---|
| Canada | 4,000 mg/kg | 1 numeric limit, 3 no quantity stated |
| European Union | 1,000 mg/kg – 3,000 mg/kg | 3 numeric limit, 3 quantum satis |
| Great Britain | 1,000 mg/kg – 2,000 mg/kg | 2 numeric limit, 1 several limits, 3 quantum satis |
| Japan | — | 1 no quantity stated |
| South Korea | — | 1 no quantity stated |
| United States | — | 1 no quantity stated |
| Codex Alimentarius | 3,000 mg/kg | 1 numeric limit, 2 GMP |
GRAS notices to the FDA
A GRAS notice is a company’s conclusion that a substance is generally recognised as safe for the use it describes. FDA’s letter responds to that conclusion, for that notifier and that use. It is not a listing in 21 CFR, and it is not counted as a US permission above. The substance and use are as FDA’s inventory words them; this site matched the notice to this page by exact name.
GRN No. 786 · Calcium propionate · Wonderful Citrus, LLC
Intended use: Intended for use as an anti-browning agent in processed fruits and vegetables
FDA’s response (2018-11-20): FDA has no questions
What it is made from
Made by neutralising propionic acid with a calcium base.
- Vegan
- Vegetarian
Compare other additives on the dietary indexes.
- CAS registry number
- 4075-81-4
- InChIKey
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L
- PubChem
- CID 19999
The two specifications, compared
The European Union sets identity and purity by regulation; JECFA publishes its own through FAO, advisory until a country adopts it. Both documents are below in full. These are the parameters each puts a number on.
| Parameter | European Union | JECFA |
|---|---|---|
| Assay | no less than 99 % | no less than 98 % |
| Loss on drying | no more than 4 % | no more than 4 % |
| Lead | no more than 5 mg/kg | no more than 5 mg/kg |
| Arsenic | no more than 3 mg/kg | — |
| Mercury | no more than 1 mg/kg | — |
One parameter differs between the two documents. A difference is not a disagreement about safety: the two are revised on their own cycles, and an assay or a drying loss can be measured against a different preparation of the substance, which is why only the contaminant ceilings are marked. Within the EU the EU's figure is the one that binds.
How the EU defines it
The legal specification an additive must meet to be sold as this E number in the EU — what it is, how it may be made, and the purity it must reach. From Commission Regulation (EU) No 231/2012.
E 282 Calcium propionate
Assay, identification and purity criteria
Description and assay
- Einecs
- 223-795-8
- Chemical name
- Calcium propionate
- Chemical formula
- C₆H₁₀O₄Ca
- Molecular weight
- 186,22
- Assay
- Content not less than 99 %, after drying for two hours at 105 °C
- Description
- White crystalline powder
Identification
- Test for propionate
- Passes test
- Test for calcium
- Passes test
- pH
- 6,0-9,0 (10 % aqueous solution)
Purity criteria
- Loss on drying
- Not more than 4 % (105 °C, 2 hours)
- Water insoluble matter
- Not more than 0,3 %
- Iron
- Not more than 50 mg/kg
- Fluoride
- Not more than 20 mg/kg
- Arsenic
- Not more than 3 mg/kg
- Lead
- Not more than 5 mg/kg
- Mercury
- Not more than 1 mg/kg
How JECFA defines it
The international specification for identity and purity, prepared by the Joint FAO/WHO Expert Committee on Food Additives and published by FAO. It is a different document from any above, written by a different body and revised on its own cycle; it is advisory, and a country adopts it or does not.
INS 282 Calcium Propionate
Synonyms: Calcium propanoate, INS No. 282 Calcium propanoate
Assay, identification and purity criteria
Description and assay
- Specification history
- Prepared at the 49th JECFA (1997), published in FNP 52 Add 5 (1997) superseding specifications prepared at the 44th JECFA (1995), published in FNP 52 Addendum 3 (1995). These specifications were reviewed and maintained at the 51st JECFA (1998) and republished in FNP 52 Add 6 (1998). ADI "not limited"established at the 17th JECFA in 1973.
- Chemical names
- Calcium propionate
- C.A.S. number
- 4075-81-4
- Chemical formula
- C 6 H 10 CaO 4
- Formula weight
- 186.22
- Assay
- Not less than 98.0% on the dried basis
- DESCRIPTION
- White crystals, powder or granules with not more than a faint odour of propionic acid
- FUNCTIONAL USES
- Preservative, antimould and antirope agent
- METHOD OF ASSAY
- Dissolve in a beaker 2.5 g of the sample, weighed to the nearest mg, in 5 ml of hot dilute hydrochloric acid TS. Cool, transfer to a 250-ml volumetric flask, dilute to volume with water, and mix. Transfer 50 ml of the solution to a 400-ml beaker, add 100 ml of water, 25 ml of sodium hydroxide TS, 40 mg of murexide indicator preparation and 3 ml of naphthol green TS. An alternative indicator is hydroxynaphthol blue, of which 0.25 g is used. In this case the naphthol green TS is omitted. Titrate with 0.05 M disodium ethylenediaminetetraacetate until the solution is deep blue in colour. Each ml of 0.05 M disodium ethylenediaminetetraacetate is equivalent to 9.311 mg of C 6 H 10 CaO 4 .
Identification
- Solubility (Vol. 4)
- Freely soluble in water, soluble in ethanol
- Test for calcium (Vol. 4)
- Passes test
- Test for propionate
- Warm the sample with sulfuric acid. The propionic acid evolved may be recognized by its odour.
- Test for alkali salt of organic acid
- Ignite the sample at a relatively low temperature. The alkaline organic acid residue effervesces with acid.
Purity criteria
- Loss on drying (Vol. 4)
- Not more than 4% (105 o , 2 h)
- pH (Vol. 4)
- 7.5 - 10.5 (1 in 10 soln)
- Water insoluble matter
- Not more than 0.3% Weigh 5 g of the sample to the nearest mg, transfer into a 100-ml beaker and add 50 ml of water. Stir until all the sample appears to be completely dissolved. Filter through a Gooch crucible, tared to an accuracy of ±0.2 mg. Rinse the beaker with 20 ml of water. Dry the crucible with its contents in a 60 o -oven to constant weight. Cool in a desiccator, weigh, and calculate as percentage.
- Fluoride (Vol. 4)
- Not more than 30 mg/kg Weigh 5 g of the sample to the nearest mg and proceed as directed in the Limit Test (Method I or III)
- Iron (Vol. 4)
- Not more than 50 mg/kg Test 0.5 g of the sample as described in the Limit Test using 2.5 ml of Iron Standard Solution (25 μg) in the control
- Lead (Vol. 4)
- Not more than 5 mg/kg Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, “Instrumental Methods.”
Every name it appears under
48 recorded names. A label may use any of them.
E number
- E282
INS number
- 282
CAS registry number
- 4075-81-4
As it appears in regulation
- Calcium propionate
Other names
- Bioban-C
- C6H10CaO4
- Ca-PROPIONATE
- calcium dipropanoate
- Calcium dipropionate
- Calcium propanoate
- Calcium propionate
- CALCIUM PROPIONATE (E 282)
- Calcium propionate;Bioban-C; Calcium dipropionate
- calciumpropionate
- CalClum propionate
- Caswell No. 151
- E 282
- EPA Pesticide Chemical Code 077701
- HSDB 907
- INS NO.282
- INS-282
- Propanoate (calcium)
- Propanoic acid, calcium salt
- Propanoic acid, calcium salt (2:1)
- propionic acid calcium
- Propionic acid calcium 1000 microg/mL in Acetonitrile:Water
- Propionic acid, calcium salt
Systematic names
- Calcium propanoate
Hazard reference values
| Type | Value | Population | Assessed by | Opinion |
|---|---|---|---|---|
| ADI | not limited | — | JECFA | 1973 |
Evidence and how bodies read it
What assessing bodies concluded
Each conclusion is paraphrased in the body's own framing, from the published opinion linked beneath it. Where bodies differ, both stand; this site does not adjudicate between them or add a view of its own.
EFSA 2014
The ANS Panel found no concern for genotoxicity or carcinogenicity for propionic acid and its salts (E 280–E 283), but concluded the database did not allow an ADI to be allocated. It concluded there would not be a safety concern from the maximum concentrations at the currently authorised uses and use levels.
Common questions
Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.
- What is E 282?
- E 282 is Calcium propionate. Calcium propionate is a mould inhibitor widely used in bread and other yeast-raised baked goods.
- What is Calcium propionate used for in food?
- It is listed as a preservative — the role Canada, Codex and the US assign it. This page shows every function each regulator records, with the citation for each.
- Where is Calcium propionate permitted?
- Of the seven regulators this site reads, Australia and New Zealand, Canada, the EU, Great Britain, Japan, South Korea, the US and the Codex standard permit it. Each permission is for named foods at named levels, not a blanket one; the table on this page gives them with citations.
- Is Calcium propionate vegan?
- Yes. Calcium propionate is not derived from animals, and is suitable for vegetarians. This page says what it is made from and how.
Sources for this page
- anz retrieved 2026-10-17
- ca retrieved 2026-10-17
- eu retrieved 2026-10-18
- gb retrieved 2026-10-18
- jp retrieved 2026-10-18
- kr retrieved 2026-10-18
- ecfr retrieved 2026-10-17
- gsfa retrieved 2026-09-07
- euspecs retrieved 2026-10-18
- jecfaspecs retrieved 2026-09-23
Full licence terms and publisher details on Sources. How this page is built and updated: Method.
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