Copper gluconate

CAS 527-09-3

Copper gluconate is a copper source in fortified foods and supplements. Copper is an essential trace element with a narrow gap between requirement and excess.

Where it is and isn’t permitted

Status of Copper gluconate by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationPermitted21 CFR 184.1260retrieved 2026-09-07
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

What it is made from

Made by reacting a copper salt with fermentation-derived gluconic acid.

  • Vegan
  • Vegetarian
CAS registry number
527-09-3
InChIKey
OCUCCJIRFHNWBP-IYEMJOQQSA-L
PubChem
CID 10692

Every name it appears under

40 recorded names. A label may use any of them.

CAS registry number

  • 527-09-3

As it appears in regulation

  • Copper gluconate

Other names

  • Bis(D-gluconato)copper
  • Bis(D-gluconato-kappaO1,kappaO2)copper
  • Bis(D-gluconato-O1,O2)copper
  • Bis(D-gluconic acid)copper(II) salt
  • C12H22CuO14
  • CCRIS 3652
  • Chelates of copper gluconate
  • COPPER (AS GLUCONATE)
  • Copper D-gluconate (1:2)
  • Copper di-D-gluconate
  • Copper gluconate
  • COPPER GLUCONATE (MART.)
  • COPPER GLUCONATE (USP MONOGRAPH)
  • Copper gluconate (USP)
  • Copper(2+) D-gluconate, (1:2)
  • Copper(2+) di(D-gluconate)
  • copper(2+) ion bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
  • Copper(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
  • Copper(II) D-gluconate
  • Copper(II) gluconate
  • Copper, bi
  • Copper, bis (D-gluconato-O(sup 1),O(sup 2))-
  • Copper, bis(D-gluconato)-
  • Copper, bis(D-gluconato-kappaO1,kappaO2)-
  • Copper, bis(D-gluconato-O1,O2)-
  • copper;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
  • CUPRIC GLUCONATE
  • Cupric gluconate monohydrate
  • CUPRUM GLUCONICUM
  • D-Gluconic acid copper (II) salt
  • Gluconate, Copper
  • Gluconates
  • Gluconic Acid Copper(II) Salt
  • Gluconic acid, copper(2+) salt
  • Gluconic acid, copper(2+) salt (2:1), D-
  • HSDB 261
  • Pleo Cup

Systematic names

  • Copper;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • ecfr retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/copper-gluconate.json