Ficin

CAS 9001-33-6

Ficin is a protein-digesting enzyme from fig latex, used as a meat tenderiser and in cheesemaking, in much the same way as papain and bromelain.

Where it is and isn’t permitted

Status of Ficin by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationPermitted21 CFR 184.1316retrieved 2026-09-07
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

What it is made from

Collected as latex from fig trees, Ficus species, then purified.

  • Vegan
  • Vegetarian
CAS registry number
9001-33-6
InChIKey
POTUGHMKJGOKRI-UHFFFAOYSA-N
PubChem
CID 129630591

Every name it appears under

9 recorded names. A label may use any of them.

CAS registry number

  • 9001-33-6

As it appears in regulation

  • Ficin

Other names

  • Debricin
  • Ficin
  • Ficus protease
  • Ficus proteinase
  • Higueroxyl delabarre
  • luoro-[(imino-lambda3-iodanyl)methylidene]-lambda3-iodane
  • POTUGHMKJGOKRI-UHFFFAOYSA-N

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • ecfr retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/ficin.json