Folic acid (folacin)
59-30-3 · 4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)- · 935E97BOY8 · Acfol (Spain) · Acide folique · Acido folico · Acidum folicum · Acifolic · Antianemia factor · Bio Science · Cytofol · Dosfolat B activ · Facid · Factor U · FOLACID · Folacin · Folaemin [Netherlands] · Folasic (Australia) · Folbal · Folcidin · Foldine · Foldine (France) · Folettes · Foliamin · folic acid · Folicare · Folicet · Folico (Italy) · Folina (Italy) · Folipac · Folsaeure · Folsan · Folsaure · Folsav · Folvite · Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, l- · Incafolic · Kyselina listova · Lexpec · Liver Lactobacillus casei factor · Megafol · Millafol · N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid · N-pteroyl-L-glutamic acid · Natur Flow · Nifolin [Denmark] · Novofolacid [Canada] · Preconceive · PteGlu · Pteroyl-L-glutamic acid · Pteroyl-L-monoglutamic acid · Pteroylglutamic acid · Pteroylmonoglutamic acid · Usaf cb-13 · Vitamin B11 · Vitamin B9 · Vitamin Bc · Vitamin Be · Vitamin M · Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L · N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid · Folic acid (folacin)CAS 59-30-3
Folic acid is the synthetic form of folate, added to flour in many countries specifically to reduce neural tube defects in pregnancy. It is one of the clearest public-health uses of a food additive.
Where it is and isn’t permitted
| Jurisdiction | Status | Scope and limits | Citation |
|---|---|---|---|
| United States | Permitted, with conditions | 21 CFR 172.345retrieved 2026-09-07 | |
| Codex Alimentarius | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. |
What it is made from
Produced by chemical synthesis. It is more stable and more readily absorbed than the folates naturally present in leafy vegetables, which is why the synthetic form is used for fortification.
- Vegan
- Vegetarian
- CAS registry number
- 59-30-3
- InChIKey
- OVBPIULPVIDEAO-LBPRGKRZSA-N
- PubChem
- CID 135398658
Every name it appears under
62 recorded names. A label may use any of them.
CAS registry number
- 59-30-3
As it appears in regulation
- Folic acid (folacin)
Other names
- 4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)-
- 935E97BOY8
- Acfol (Spain)
- Acide folique
- Acido folico
- Acidum folicum
- Acifolic
- Antianemia factor
- Bio Science
- Cytofol
- Dosfolat B activ
- Facid
- Factor U
- FOLACID
- Folacin
- Folaemin [Netherlands]
- Folasic (Australia)
- Folbal
- Folcidin
- Foldine
- Foldine (France)
- Folettes
- Foliamin
- folic acid
- Folicare
- Folicet
- Folico (Italy)
- Folina (Italy)
- Folipac
- Folsaeure
- Folsan
- Folsaure
- Folsav
- Folvite
- Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, l-
- Incafolic
- Kyselina listova
- Lexpec
- Liver Lactobacillus casei factor
- Megafol
- Millafol
- N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
- N-pteroyl-L-glutamic acid
- Natur Flow
- Nifolin [Denmark]
- Novofolacid [Canada]
- Preconceive
- PteGlu
- Pteroyl-L-glutamic acid
- Pteroyl-L-monoglutamic acid
- Pteroylglutamic acid
- Pteroylmonoglutamic acid
- Usaf cb-13
- Vitamin B11
- Vitamin B9
- Vitamin Bc
- Vitamin Be
- Vitamin M
Systematic names
- Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
- N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
Hazard reference values
No reference value for this substance in the sources we hold.
Evidence and how bodies read it
Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.
Sources for this page
- ecfr retrieved 2026-09-07
Full licence terms and publisher details on Sources. How this page is built and updated: Method.
Machine-readable:/api/v1/additives/folic-acid-folacin.json