Glucose isomerase from Actinoplanes missouriensis
Glucose isomerase from Actinoplanes missouriensis · Xylose isomeraseGlucose isomerase converts glucose into fructose, which is the step that turns corn syrup into high-fructose corn syrup. It is usually used immobilised on a carrier, so that syrup can be run over it continuously.
Where it is and isn’t permitted
| Jurisdiction | Status | Scope and limits | Citation |
|---|---|---|---|
| Australia and New Zealand | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Canada | No listing matchedHealth Canada’s lists name additives without E or INS numbers, so this site matches them by exact name. A substance listed there under a name this site does not recognise has no row here. | ||
| European Union | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Great Britain | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Japan | No listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance. | ||
| South Korea | No listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance. | ||
| United States | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. | ||
| Codex Alimentarius | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. |
What it is made from
Produced by fermenting Actinoplanes missouriensis. The immobilised preparation is supplied as off-white to brown granules.
How JECFA defines it
The international specification for identity and purity, prepared by the Joint FAO/WHO Expert Committee on Food Additives and published by FAO. It is a different document from any above, written by a different body and revised on its own cycle; it is advisory, and a country adopts it or does not.
Glucose Isomerase from Actinoplanes missouriensis
Synonyms: Xylose isomerase
Assay, identification and purity criteria
Description and assay
- Specification history
- Prepared at the 28th JECFA (1984), published in FNP 31/2 (1984) and in FNP 52 (1992). An ADI 'acceptable' was established at the 29th JECFA (1985)
- SOURCES
- Produced by the controlled fermentation of Actinoplanes missouriensis
- Active principles
- Xylose isomerase (glucose isomerase)
- Systematic names and numbers
- D-Xylose ketol-isomerase (EC 5.3.1.5)
- Reactions catalyzed
- D-Xylose and D-glucose are converted to D-xylulose and D-fructose, respectively
- DESCRIPTION
- Off-white to brown granules (immobilized preparation) or liquids, insoluble in water (granules), ethanol, chloroform and ether The immobilized preparations are rendered insoluble in water by treatment with gelatine (carrier) and glutaraldehyde (immobilization agent).
- FUNCTIONAL USES
- Enzyme preparation Used in the preparation of high fructose corn syrup and other fructose starch syrups.
- GENERAL SPECIFICATIONS
- Must conform to the General Specifications for Enzyme Preparations used in Food Processing (see Volume Introduction)
Identification
- Glucose isomerase activity (Vol. 4)
- The sample shows glucose isomerase activity
Purity criteria
- Glutaraldehyde (Vol. 4)
- Passes Limit Test for Glutaraldehyde from Immobilized Glucose Isomerases crosslinked with Glutaraldehyde
Every name it appears under
2 recorded names. A label may use any of them.
Other names
- Glucose isomerase from Actinoplanes missouriensis
- Xylose isomerase
Hazard reference values
No reference value for this substance in the sources we hold.
Evidence and how bodies read it
Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.
Sources for this page
- jecfaspecs retrieved 2026-09-23
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