Mannitol manufactured by fermentation

E number E421(ii)

Listed as a sweetener by the EU.

Listed as sweeteners (EU)

Mannitol manufactured by fermentation is mannitol made by aerobic fermentation with the yeast Zygosaccharomyces rouxii, the EU's second specification under E 421. The EU's specification (Regulation 231/2012) numbers it E 421(ii), a form under the E 421 listing in Annex II, Mannitol.

Where it is and isn’t permitted

Status of Mannitol manufactured by fermentation by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
Australia and New ZealandFood Standards Australia New ZealandNo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.Related listing with permitted uses here: Mannitol (E421). This site cannot tell whether that listing covers this exact form.
CanadaHealth CanadaNo listing matchedHealth Canada’s lists name additives without E or INS numbers, so this site matches them by exact name. A substance listed there under a name this site does not recognise has no row here.Related listing with permitted uses here: Mannitol (E421). This site cannot tell whether that listing covers this exact form.
European UnionEuropean Commission / EFSAPermitted, with conditions

95 food categories

Show every food category
  • 1.3 unflavoured fermented milk products heat-treated after fermentation — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 1.4 flavoured fermented milk products including heat-treated products — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 1.4 flavoured fermented milk products including heat-treated products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced products or with no added sugar.
  • 1.6.3 other creams — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 1.7.1 unripened cheese excluding products falling in category 16Authorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except mozzarella.
  • 1.7.5 processed cheese — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except E 425 ML = 10000 mg/kg; E 620 to E 625, ML =10000 mg/kg individually or in combination, expressed as glutamic acid;E 626 to E 635, ML = 500 mg/kg individually or in combination, expressedas guanylic acid.
  • 1.7.6 cheese products (excluding products falling in category 16) — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 1.8 Dairy analogues, including beverage whiteners — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 10.2 processed eggs and egg products — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML =10000 mg/kg individually or in combination, expressed as glutamic acid;E 626 to E 635, ML = 500 mg/kg individually or in combination, expressedas guanylic acid.
  • 11.2 Other sugars and syrups — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 11.4.1 table-top sweeteners in liquid form — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 11.4.2 table-top sweeteners in powder form — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 11.4.3 table-top sweeteners in tablets — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 12.1.2 salt substitutes — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.2.2 Seasonings and condiments — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.3 Vinegars and diluted acetic acid (diluted with water to 4-30 % by volume) — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.4 Mustard — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.4 Mustard — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 12.5 Soups and broths — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.6 Sauces — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.6 Sauces — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 12.7 Salads and savoury-based sandwich spreads — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.8 Yeast and yeast products — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 12.9 Protein products excluding products covered in category 1 8 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 13.1 foods for infants and young childrenAuthorised under E 421, Mannitol. 1 000 times more than vitamin B12, 3 mg/kg total carry-over.
  • 13.2 Foods for special medical purposes as defined by Regulation (EU) No 609/2013 (excluding products from food category 13.1.5.) — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 13.2 Foods for special medical purposes as defined by Regulation (EU) No 609/2013 (excluding products from food category 13.1.5.) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 13.3 Total diet replacement for weight control food as defined by Regulation (EU) No 609/2013 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 13.3 Total diet replacement for weight control food as defined by Regulation (EU) No 609/2013 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 14.1.2 Fruit juices as defined by Directive 2001/112/EC and vegetable juicesAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. only vegetable juices.
  • 14.1.3 Fruit nectars as defined by Directive 2001/112/EC and vegetable nectars and similar productsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. only vegetable nectars, E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.1.4 Flavoured_drinksAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E 421, E 953, E 965, E 966 and E 967 may not be used E 968 may not be used except where specifically provided for in this food category.
  • 14.1.5.2 otherAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. excluding unflavoured leaf tea; including flavoured instant coffee; E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used in drinks.
  • 14.2.3 Cider and perryAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.4 Fruit wine and made wineAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.5 MeadAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.6 Spirit drinks as defined in Regulation (EU) 2019/787Authorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except whisky or whiskey; E 420, E421, E 953, E 965, E 966, E 967 and E 968 may not be used except in liqueurs.
  • 14.2.7.1 Aromatised winesAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.7.2 Aromatised wine-based drinksAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.7.3 Aromatised wine-product cocktailsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.8 Other alcoholic beverages including mixtures of alcoholic beverages with non-alcoholic beverages and other alcoholic beverages based on distilled alcohol with alcoholic strength by volume less than 15 %Authorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 420, E421, E 953, E 965, E 966, E 967 and E 968 may not be used.
  • 15.1 Potato- cereal- flour- or starch-based snacks — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 15.2 Processed nuts — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 16 Desserts excluding products covered in category 1 3 and 4 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 16 Desserts excluding products covered in category 1 3 and 4 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 17.1 food supplements supplied in a solid form excluding food supplements for infants and young children’,Authorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 410, E 412, E 415, E 417 and E 425 may not be used to produce dehydrated food supplements intended to rehydrate on ingestion.
  • 17.1 food supplements supplied in a solid form excluding food supplements for infants and young children’, — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 17.2 food supplements supplied in a liquid form excluding food supplements for Infants and young children — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 17.2 food supplements supplied in a liquid form excluding food supplements for Infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 18 Processed foods not covered by categories 1 to 17 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 18.1 Processed foods not covered by categories 18.2 and 18.3, excluding foods for infants and young children — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 18.2 Meal replacement for weight control as referred to in Commission Regulation (EU) No 432/2012 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 18.2 Meal replacement for weight control as referred to in Commission Regulation (EU) No 432/2012 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 18.3 Food specially produced to reduce the gluten content of gluten-containing ingredients or substitute the gluten-containing ingredientsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. Including dry pasta.
  • 18.3 Food specially produced to reduce the gluten content of gluten-containing ingredients or substitute the gluten-containing ingredients — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis.
  • 2.2.2 Other fat and oil emulsions including spreads as defined by Regulation (EC) No 1234/2007 and liquid emulsions — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 2.3 Vegetable oil pan spray — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 3 edible ices — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 3 edible ices — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.1 dried fruit and vegetablesAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. E 410, E 412, E 415 and E 417 may not be used to produce dehydrated foods intended to rehydrate on ingestion.
  • 4.2.2 fruit and vegetables in vinegar oil or brine — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 4.2.4.1 fruit and vegetable preparations excluding compote — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 4.2.4.1 fruit and vegetable preparations excluding compote — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar, with the exception of those intended for the manufacture of fruit-juice based drinks.
  • 4.2.5.1 Extra jam and extra jelly as defined by Directive 2001/113/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced jams, jellies, marmalades or with no added sugar.
  • 4.2.5.2 Jam, jellies and marmalades and sweetened chestnut puree as defined by Directive 2001/113/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.5.3 other similar fruit or vegetable spreads — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.5.4 nut butters and nut spreads — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 4.2.6 processed potato products — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 5.1 Cocoa and chocolate products as covered by Directive 2000/36/ECAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. only energy-reduced or with no added sugars.
  • 5.1 Cocoa and chocolate products as covered by Directive 2000/36/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 5.2 Other confectionery including breath freshening micro-sweetsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. The substances listed under numbers E 400, E 401, E 402, E 403, E 404, E 406, E 407, 407a, E 410, E 412, E 413, E 414, E 415, E 417, E 418, E 425 and E 440 may not be used in jelly mini-cups, defined, for the purpose of this Regulation, as jelly confectionery of a firm consistence, contained in semi rigid mini-cups or mini-capsules, intended to be ingested in a single bite by exerting pressure on the mini-cups or mini-capsule to project the confectionery into the mouth; E 410, E 412, E 415 E 417 may not be used to produce dehydrated foods intended to rehydrate on ingestion. E425 may not be used in jelly confectionery.
  • 5.2 Other confectionery including breath freshening micro-sweets — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only with no added sugar.
  • 5.3 chewing gum — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 5.3 chewing gum — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only with no added sugar.
  • 5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only decorations, coatings and fillings with not added sugar.
  • 6.2.2 starches — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.3 breakfast cereals — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.3 breakfast cereals — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only breakfast cereals or cereal-based products, energy reduced or with no added sugar.
  • 6.4.2 Dry pasta — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.4.4 Potato GnocchiAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except fresh refrigerated potato gnocchi.
  • 6.4.5 fillings of stuffed pasta (ravioli and similar) — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.5 Noodles — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.6 Batters — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 6.7 pre-cooked or processed cereals — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 7.1 Bread and rollsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except products in 7.1.1 and 7.1.2.
  • 7.2 Fine bakery wares — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 7.2 Fine bakery wares — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 8.3.1 Non-heat-treated processed meat — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 8.3.2 Heat-treated meat productsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. except foie gras, foie gras entier, blocs de foie gras, Libamáj, libamáj egészben, libamáj tömbben.
  • 8.3.3 Casings and coatings and decorations for meat — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 9.1.1 Unprocessed fish — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only frozen and deep-frozen unprocessed fish for purposes other than sweetening.
  • 9.1.2 Unprocessed molluscs and crustaceans — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV, Polyols. quantum satis. only frozen and deep-frozen unprocessed crustaceans, molluscs and cephalopods; for purposes other than sweetening.
  • 9.2 Processed fish and fishery products including molluscs and crustaceans — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. ML = quantum satis; except E 425 ML = 10000 mg/kg; E 620 to E 625, ML = 10000 mg/kg individually or in combination, expressed as glutamic acid; E 626 to E 635, ML = 500 mg/kg individually or in combination, expressed as guanylic acid.
  • 9.3 fish roeAuthorised under E 421, Mannitol. Permitted as a member of Group I, Additives. only processed fish roe.
Regulation (EC) No 1333/2008, Annex IIand 94 further provisionsretrieved 2026-10-18
Great BritainFood Standards Agency / Food Standards ScotlandPermitted, with conditions

91 food categories

Show every food category
  • 1.3 Unflavoured fermented milk products, heat-treated after fermentation — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 1.4 Flavoured fermented milk products including heat-treated products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 1.4 Flavoured fermented milk products including heat-treated products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced products or with no added sugar.
  • 1.6.3 Other creams — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 1.7.1 Unripened cheese excluding products falling in category 16 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). except mozzarella.
  • 1.7.5 Processed cheese — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 1.7.6 Cheese products (excluding products falling in category 16) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 1.8 Dairy analogues, including beverage whiteners — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 10.2 Processed eggs and egg products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 11.2 Other sugars and syrups — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 11.4.1 Table-top sweeteners in liquid form — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 11.4.2 Table-top sweeteners in powder form — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 11.4.3 Table-top sweeteners in tablets — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 12.1.2 Salt substitutes — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.2.2 Seasonings and condiments — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.3 Vinegars and diluted acetic acid (diluted with water to 4-30 % by volume) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.4 Mustard — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.4 Mustard — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 12.5 Soups and broths — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.6 Sauces — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.6 Sauces — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 12.7 Salads and savoury based sandwich spreads — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.8 Yeast and yeast products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 12.9 Protein products, excluding products covered in category 1.8 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 13.2 Dietary foods for special medical purposes defined in Directive 1999/21/EC (excluding products from food category 13.1.5) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 13.2 Dietary foods for special medical purposes defined in Directive 1999/21/EC (excluding products from food category 13.1.5) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 13.3 Dietary foods for weight control diets intended to replace total daily food intake or an individual meal (the whole or part of the total daily diet) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 13.3 Dietary foods for weight control diets intended to replace total daily food intake or an individual meal (the whole or part of the total daily diet) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 13.4 Foods suitable for people intolerant to gluten as defined by Commission Regulation (EC) No 41/2009 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). including dry pasta.
  • 13.4 Foods suitable for people intolerant to gluten as defined by Commission Regulation (EC) No 41/2009 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 14.1.2 Fruit juices as defined by Directive 2001/112/EC and vegetable juices — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). only vegetable juices.
  • 14.1.3 Fruit nectars as defined by Directive 2001/112/EC and vegetable nectars and similar products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). only vegetable nectars, E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.1.4 Flavoured drinks — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E 421, E 953, E 965, E 966 and E 967 may not be used E 968 may not be used except where specifically provided for in this food category.
  • 14.1.5.2 Other — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). excluding unflavoured leaf tea; including flavoured instant coffee; E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used in drinks.
  • 14.2.3 Cider and perry — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.4 Fruit wine and made wine — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.5 Mead — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.6 Spirit drinks as defined in Regulation (EC) No 110/2008 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). except whisky or whiskey; E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used except in liqueurs.
  • 14.2.7.1 Aromatised wines — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.7.2 Aromatised wine-based drinks — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.7.3 Aromatised wine-product cocktails — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 14.2.8 Other alcoholic drinks including mixtures of alcoholic drinks with non-alcoholic drinks and spirits with less than 15 % of alcohol — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 420, E421, E 953, E965, E 966, E 967 and E 968 may not be used.
  • 15.1 Potato-, cereal-, flour- or starch-based snacks — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 15.2 Processed nuts — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 16 Desserts excluding products covered in categories 1, 3 and 4 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 16 Desserts excluding products covered in categories 1, 3 and 4 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 17.1 Food supplements supplied in a solid form, excluding food supplements for infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 410, E 412, E 415, E 417 and E 425 may not be used to produce dehydrated food supplements intended to rehydrate on ingestion.
  • 17.1 Food supplements supplied in a solid form, excluding food supplements for infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 17.2 Food supplements supplied in a liquid form, excluding food supplements for infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 17.2 Food supplements supplied in a liquid form, excluding food supplements for infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis.
  • 18 Processed foods not covered by categories 1 to 17, excluding foods for infants and young children — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 2.2.2 Other fat and oil emulsions including spreads as defined by Regulation (EC) No 1234/2007 and liquid emulsions — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 2.3 Vegetable oil pan spray — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 3 Edible ices — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 3 Edible ices — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.1 Dried fruit and vegetables — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). E 410, E 412, E 415 E 417 may not be used to produce dehydrated foods intended to rehydrate on ingestion.
  • 4.2.2 Fruit and vegetables in vinegar, oil, or brine — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 4.2.4.1 Fruit and vegetable preparations excluding compote — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 4.2.4.1 Fruit and vegetable preparations excluding compote — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar, with the exception of those intended for the manufacture of fruit-juice based drinks.
  • 4.2.5.1 Extra jam and extra jelly as defined by Directive 2001/113/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced jams, jellies, marmalades or with no added sugar.
  • 4.2.5.2 Jam, jellies and marmalades and sweetened chestnut puree as defined by Directive 2001/113/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.5.3 Other similar fruit or vegetable spreads — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 4.2.5.4 Nut butters and nut spreads — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 4.2.6 Processed potato products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 5.1 Cocoa and chocolate products as covered by Directive 2000/36/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). only energy-reduced or with no added sugar.
  • 5.1 Cocoa and chocolate products as covered by Directive 2000/36/EC — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 5.2 Other confectionery including breath refreshening microsweets — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). The substances listed under numbers E 400, E 401, E 402, E 403, E 404, E 406, E 407, 407a, E 410, E 412, E 413, E 414, E 415, E 417, E 418, E 425 and E 440 may not be used in jelly mini-cups, defined, for the purpose of this Regulation, as jelly confectionery of a firm consistence, contained in semi rigid mini-cups or mini-capsules, intended to be ingested in a single bite by exerting pressure on the mini-cups or mini-capsule to project the confectionery into the mouth; E 410, E 412, E 415 E 417 may not be used to produce dehydrated foods intended to rehydrate on ingestion. E425 may not be used in jelly confectionery.
  • 5.2 Other confectionery including breath refreshening microsweets — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. (1) quantum satis: only with no added sugar; (2) quantum satis: only starch-based confectionery energy-reduced or with no added sugar; (3) quantum satis: sandwich spreads made with a base of cocoa, milk, dried fruit or fat; energy reduced or with no added sugar; (4) quantum satis: only cocoa-based or dried fruit-based confectionery, energy-reduced or with no added sugar; (5) quantum satis: only for crystallised fruit, energy-reduced or with no added sugar.
  • 5.3 Chewing gum — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 5.3 Chewing gum — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only with no added sugar.
  • 5.4 Decorations, coatings and fillings, except fruit based fillings covered by category 4.2.4 — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 5.4 Decorations, coatings and fillings, except fruit based fillings covered by category 4.2.4 — several limitsAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. (1) quantum satis: only decorations, coatings and fillings with not added sugar; (2) quantum satis: only sauces.
  • 6.2.2 Starches — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 6.3 Breakfast cereals — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 6.3 Breakfast cereals — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only breakfast cereals or cereal-based products, energy-reduced or with no added sugar.
  • 6.4.2 Dry pasta — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). only gluten free and/or pasta intended for hypoproteic diets in accordance with Directive 2009/39/EC.
  • 6.4.4 Potato gnocchi — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). except fresh refrigerated potato gnocchi.
  • 6.4.5 Fillings of stuffed pasta (ravioli and similar) — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 6.5 Noodles — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 6.6 Batters — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 6.7 Pre-cooked or processed cereals — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 7.1 Bread and rolls — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). except products in 7.1.1 and 7.1.2.
  • 7.2 Fine bakery wares — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 7.2 Fine bakery wares — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only energy-reduced or with no added sugar.
  • 8.3.1 Non-heat-treated meat products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 8.3.2 Heat-treated meat products — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). except foie gras, foie gras entier, blocs de foie gras, Libamáj, libamáj egészben, libamáj tömbben.
  • 8.3.3 Casings and coatings and decorations for meat — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 9.1.1 Unprocessed fish — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only frozen and deep-frozen unprocessed fish for purposes other than sweetening.
  • 9.1.2 Unprocessed molluscs and crustaceans — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group IV: Polyols. quantum satis. only frozen and deep-frozen unprocessed crustaceans, molluscs and cephalopods; for purposes other than sweetening.
  • 9.2 Processed fish and fishery products including mollusks and crustaceans — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening).
  • 9.3 Fish roe — quantum satisAuthorised under E 421, Mannitol. Permitted as a member of Group I. Maximum level: Quantum satis (for purpose other than sweetening). only processed fish roe.
Assimilated Regulation (EC) No 1333/2008, Annex II (as at 28 June 2024)and 90 further provisionsretrieved 2026-10-18
JapanConsumer Affairs AgencyNo listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance.Related listing with permitted uses here: Mannitol (E421). This site cannot tell whether that listing covers this exact form.
South KoreaMinistry of Food and Drug SafetyNo listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance.Related listing with permitted uses here: Mannitol (E421). This site cannot tell whether that listing covers this exact form.
United StatesFood and Drug AdministrationNot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

How much is permitted

A listing usually limits the quantity as well as the food. Only one of the forms that takes is a figure: quantum satis and good manufacturing practice permit the amount the technological effect requires and no more, which is a limit rather than the absence of one. Figures below are the range across every food category this page is listed in, and categories differ between regulators — see how much is permitted.

European Union—46 several limits, 26 quantum satis, 23 no quantity stated
Great Britain—2 several limits, 89 quantum satis

No regulator sets a figure for Mannitol manufactured by fermentation. That is not an absence of control: where the listing says quantum satis or good manufacturing practice, the quantity is limited to what the effect requires.

What a label must say

Words a food containing Mannitol manufactured by fermentation is obliged to carry, quoted from the instrument that imposes them. A required statement is a fact about the regulation, not a finding about the substance — every rule below applies where the additive is authorised.

Every rule collected at what a label must say.

What it is made from

The sources cited here do not say how it is made, so this page claims no route.

How the EU defines it

The legal specification an additive must meet to be sold as this E number in the EU — what it is, how it may be made, and the purity it must reach. From Commission Regulation (EU) No 231/2012.

E 421(ii) Mannitol manufactured by fermentation

Manufactured by discontinuous fermentation under aerobic conditions using a conventional strain of the yeast Zygosaccharomyces rouxii. The part of the product which is not mannitol is mainly composed of sorbitol, maltitol and isomalt.

Synonyms: D-mannitol

Assay, identification and purity criteria

Description and assay

Einecs
200-711-8
Chemical name
D-mannitol
Chemical formula
C₆H₁₄O₆
Molecular weight
182,2
Assay
Not less than 99 % on the dried basis
Description
White, odourless crystalline powder

Identification

Solubility
Soluble in water, very slightly soluble in ethanol, practically insoluble in ether
Melting range
Between 164 and 169 °C
Infrared absorption spectrometry
Comparison with a reference standard e.g. EP or USP
Specific rotation
[α]D ²⁰ + 23° to + 25° (borate solution)
pH
Between 5 and 8 Add 0,5 ml of a saturated solution of potassium chloride to 10 ml of a 10 % w/v solution of the sample, then measure the pH

Purity criteria

Arabitol
Not more than 0,3 %
Water content
Not more than 0,5 % (Karl Fischer Method)
Conductivity
Not more than 20 μS/cm (on 20 % dry solids solution) at temperature 20 °C
Reducing sugars
Not more than 0,3 % (expressed as glucose)
Total sugars
Not more than 1 % (expressed as glucose)
Lead
Not more than 1 mg/kg
Microbiological criteria: Aerobic mesophilic bacteria
Not more than 1 000 colonies per gram
Microbiological criteria: Coliforms
Absent in 10 g
Microbiological criteria: Salmonella spp.
Absent in 25 g
Microbiological criteria: Escherichia coli
Absent in 10 g
Microbiological criteria: Staphylococcus aureus
Absent in 10 g
Microbiological criteria: Pseudomonas aeruginosa
Absent in 10 g
Microbiological criteria: Moulds
Not more than 100 colonies per gram
Microbiological criteria: Yeasts
Not more than 100 colonies per gram

Commission Regulation (EU) No 231/2012, Annex, E 421(ii), (ii) MANNITOL MANUFACTURED BY FERMENTATION

Every name it appears under

3 recorded names. A label may use any of them.

E number

  • E421

As it appears in regulation

  • Mannitol

Other names

  • Mannitol manufactured by fermentation

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.

Common questions

Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.

What is E 421(ii)?
E 421(ii) is Mannitol manufactured by fermentation. Mannitol manufactured by fermentation is mannitol made by aerobic fermentation with the yeast Zygosaccharomyces rouxii, the EU's second specification under E 421. The EU's specification (Regulation 231/2012) numbers it E 421(ii), a form under the E 421 listing in Annex II, Mannitol.
What is Mannitol manufactured by fermentation used for in food?
It is listed as a sweetener — the role the EU assigns it. This page shows every function each regulator records, with the citation for each.
Where is Mannitol manufactured by fermentation permitted?
Of the seven regulators this site reads, the EU and Great Britain permit it. Each permission is for named foods at named levels, not a blanket one; the table on this page gives them with citations.

Sources for this page

  • eu retrieved 2026-10-18
  • gb retrieved 2026-10-18
  • euspecs retrieved 2026-10-18

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable: a JSON record of this additive is given on request —how to ask for access.

Follow changes to Mannitol manufactured by fermentation:Atom feed — regulatory events, and any change the weekly refresh detects in its provisions.