Morpholine

CAS 110-91-8

Morpholine is a component of the wax coatings applied to fresh fruit, acting as the agent that lets the wax emulsify in water.

Where it is and isn’t permitted

Status of Morpholine by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationPermitted, with conditions21 CFR 172.235retrieved 2026-09-07
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

What it is made from

Produced by chemical synthesis from diethylene glycol and ammonia.

  • Vegan
  • Vegetarian
CAS registry number
110-91-8
InChIKey
YNAVUWVOSKDBBP-UHFFFAOYSA-N
PubChem
CID 8083

Every name it appears under

55 recorded names. A label may use any of them.

CAS registry number

  • 110-91-8
  • 138048-80-3

As it appears in regulation

  • Morpholine

Other names

  • 1-Oxa-4-azacyclohexane
  • 1-Oxa-4-azacyclohexane; Tetrahydro-2H-1,4-oxazine
  • 2H-1,4-Oxazine, tetrahydro-
  • 4-27-00-00015 (Beilstein Handbook Reference)
  • 4H-1, tetrahydro-
  • 4H-1,4-Oxazine, tetrahydro-
  • 8B2ZCK305O
  • BASF 238
  • BRN 0102549
  • CAS-110-91-8
  • Caswell No. 584
  • CCRIS 2482
  • Diethylene imidoxide
  • Diethylene oximide
  • Diethyleneimide oxide
  • Diethylenimide oxide
  • Drewamine
  • EPA Pesticide Chemical Code 054701
  • HSDB 102
  • InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H
  • Molsidomine EP Impurity E
  • morphline
  • morpho line
  • morpholin
  • Morpholine
  • Morpholine (BASF)
  • Morpholine on Rasta Resin
  • Morpholine purified by distillation from glass
  • Morpholine(Discontinued,See C4X-20707)
  • Morpholine, ACS reagent, >=99.0%
  • Morpholine, analytical standard
  • Morpholine, p.a., ACS reagent, 99.0%
  • MORPHOLINE, PRACT
  • Morpholine, purified by redistillation, >=99.5%
  • Morpholine, ReagentPlus(R), >=99%
  • MORPHOLINE,REAG
  • morpholine-
  • Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E
  • p-Isoxazine, tetrahydro-
  • Polymer bonded morpholine
  • Tetrahydro-1,4-isoxazine
  • Tetrahydro-1,4-oxazine
  • Tetrahydro-2H-1,4-oxazine
  • Tetrahydro-4H-1,4-Oxazine
  • Tetrahydro-4H-1-4-oxazine
  • Tetrahydro-p-isoxazine
  • Tetrahydro-p-oxazine
  • Tetryhydro-2H-1,4-oxazine
  • WLN: T6M DOTJ

Systematic names

  • morpholine
  • ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading
  • StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked

Hazard reference values

Values set by assessing bodies. A body that has not set a value is not listed here.
TypeValuePopulationAssessed byOpinion
ADI1consumersEFSA2023

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • ecfr retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/morpholine.json