Potassium gluconate

INS 577

Used as an acidity regulator — Codex also lists it as sequestrant.

Potassium gluconate is a potassium source, sequestrant and acidity regulator, used in reduced-sodium foods and supplements.

Where it is and isn’t permitted

Status of Potassium gluconate by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationNot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.
Codex AlimentariusCodex Alimentarius Commission / JECFAPermitted, with conditions

1 food category

no numerical limit (good manufacturing practice)

CXS 192-1995 Table Three, INS 577and 1 further provisionretrieved 2026-09-07

What it is made from

Made by neutralising fermentation-derived gluconic acid with a potassium source.

  • Vegan
  • Vegetarian
InChIKey
HLCFGWHYROZGBI-JJKGCWMISA-M
PubChem
CID 16760467

Every name it appears under

38 recorded names. A label may use any of them.

INS number

  • 577

CAS registry number

  • 299-27-4

Other names

  • 12H3K5QKN9
  • 2,3,4,5,6-Pentahydroxycaproic acid potassium salt
  • CAS-299-27-4
  • D-Gluconic acid (potassium) (Standard)
  • d-gluconic acid potassium
  • D-Gluconic acid potassium salt
  • D-Gluconic acid, monopotassium salt
  • D-Gluconic acid, potassium salt (1:?)
  • Gluconic acid potassium salt
  • Gluconic acid, monopotassium salt
  • Gluconsan K
  • Gluconsan-K (TN)
  • HSDB 3165
  • INS NO.577
  • INS-577
  • K-Iao
  • Kali gluconicum
  • Kalium Gluconate
  • Kalium-beta
  • Kaon
  • Kaon elixir
  • Katorin
  • Monopotassium D-gluconate
  • Potalium
  • Potasoral
  • potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
  • Potassium D-gluconate
  • Potassium D-gluconate, >=99%
  • POTASSIUM GLUCONATE
  • Potassium gluconate (JAN/USP)
  • Potassium gluconate, meets USP testing specifications, anhydrous
  • Potassium gluconate, Pharmaceutical Secondary Standard; Certified Reference Material
  • Potassium gluconate, United States Pharmacopeia (USP) Reference Standard
  • PotassiumD-gluconate
  • Potassuril
  • Sirokal

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • gsfa retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/potassium-gluconate.json