THBP

THBP, 2,4,5-trihydroxybutyrophenone, is a synthetic antioxidant used to protect fats and oils from rancidity.

Where it is and isn’t permitted

Status of THBP by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
United StatesFood and Drug AdministrationPermitted, with conditions21 CFR 172.190retrieved 2026-09-07
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

What it is made from

Produced by chemical synthesis from phenol intermediates.

  • Vegan
  • Vegetarian
InChIKey
SRUQARLMFOLRDN-UHFFFAOYSA-N
PubChem
CID 15008

Every name it appears under

25 recorded names. A label may use any of them.

CAS registry number

  • 1421-63-2

As it appears in regulation

  • THBP

Other names

  • 1 - (2,4,5-trihydroxyphenyl) 1-butanone
  • 1-(2,4,5-Trihydroxyphenyl)-1-butanone
  • 1-(2,4,5-trihydroxyphenyl)butan-1-one
  • 1-butanone, 1-(2,4,5-trihydroxyphenyl)
  • 1-Butanone, 1-(2,4,5-trihydroxyphenyl)-
  • 1-Butanone,4,5-trihydroxyphenyl)-
  • 2 inverted exclamation marka,4 inverted exclamation marka,5 inverted exclamation marka-Trihydroxybutyrophenone
  • 2',4',5'-Trihydroxy-Butyrophenone
  • 2',4',5'-Trihydroxybutyrophenone
  • 2',4',5'-Trihydroxybutyrophenone, 8CI
  • 2',5'-Trihydroxybutyrophenone
  • 2,4,5-TRIHYDROXYBUTYROPHENONE
  • 2,5-Trihydroxybutyrophenone
  • 4-08-00-02753 (Beilstein Handbook Reference)
  • 5-Butanoyl-1,2,4-benzeneetriol
  • BRN 2577028
  • Butyrophenone, 2',4',5'-trihydroxy-
  • Butyrophenone,4',5'-trihydroxy-
  • CCRIS 6281
  • HSDB 4288
  • Thbp
  • USAF EK
  • WLN: QR BQ DQ EV3

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

  • ecfr retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/thbp.json