Cyclohexane
110-82-7 · 12217-02-6 · 48K5MKG32S · Acid red 300 · ASTM Method D5191 Vapor Pressure - 22.5 kPa (3.26 psi) · Benzene hexahydride · Benzene, hexahydro- · Benzenehexahydride · CAS-110-82-7 · Caswell No. 269 · CCRIS 3928 · Cicloesano · Ciclohexano · cyclo-hexane · Cyclohexaan · Cyclohexan · Cyclohexane · Cyclohexane 2000 microg/mL in Methanol · Cyclohexane packed in clear glass ampule · Cyclohexane Solution in Methanol, 1000ug/mL · Cyclohexane Solution in Methanol, 100ug/mL · Cyclohexane, ACS Grade · Cyclohexane, ACS reagent, >=99% · Cyclohexane, ACS spectrophotometric grade, >=99% · Cyclohexane, analytical standard · Cyclohexane, anhydrous, 99.5% · Cyclohexane, AR, >=99.5% · Cyclohexane, for HPLC · Cyclohexane, for HPLC, >=99.7% · Cyclohexane, for HPLC, >=99.9% · Cyclohexane, HPLC Grade · Cyclohexane, HPLC grade, >=99.9% · Cyclohexane, HPLC UV/IR isocratic grade, min. 99.9% · Cyclohexane, JIS special grade · Cyclohexane, Laboratory Reagent, >=99.8% · Cyclohexane, LR, >=99% · Cyclohexane, p.a., 99.0% · Cyclohexane, p.a., ACS reagent, 99.0% · Cyclohexane, Pharmaceutical Secondary Standard; Certified Reference Material · Cyclohexane, puriss. p.a., ACS reagent, >=99.5% (GC) · Cyclohexane, puriss., >=99.5% (GC) · Cyclohexane, SAJ first grade, >=99.0% · Cyclohexane, UV HPLC spectroscopic, 99.5% · CYCLOHEXANE- D12 · Cykloheksan · cylcohexane · cylohexane · EPA Pesticide Chemical Code 025901 · ghl.PD_Mitscher_leg0.242 · hexahydro-Benzene · Hexahydrobenzene · Hexamethylene · Hexanaphthene · HSDB 60 · InChI=1/C6H12/c1-2-4-6-5-3-1/h1-6H · Phthalate ester quality control substance in polyvinyl chloride · RCRA waste no. U056 · RCRA waste number U056 · WLN: L6TJ · ZyklohexanCAS 110-82-7
Listed as a solvent by the US.
Listed as solvents and vehicles (US)
- United States: Solvent or vehicle — FDA, Substances Added to Food: CYCLOHEXANE
Cyclohexane is a colourless flammable liquid used as an extraction solvent. Like the other solvents JECFA specifies, it is meant to be removed from the food it was used on, and the specification governs its purity rather than a level in food.
Where it is and isn’t permitted
| Jurisdiction | Status | Scope and limits | Citation |
|---|---|---|---|
| Australia and New Zealand | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Canada | No listing matchedHealth Canada’s lists name additives without E or INS numbers, so this site matches them by exact name. A substance listed there under a name this site does not recognise has no row here. | ||
| European Union | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Great Britain | No listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it. | ||
| Japan | No listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance. | ||
| South Korea | No listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance. | ||
| United States | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. | ||
| Codex Alimentarius | Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited. |
What it is made from
Made by hydrogenating benzene, from petroleum feedstocks.
- Vegan
- Vegetarian
Compare other additives on the dietary indexes.
- CAS registry number
- 110-82-7
- InChIKey
- XDTMQSROBMDMFD-UHFFFAOYSA-N
- PubChem
- CID 8078
How JECFA defines it
The international specification for identity and purity, prepared by the Joint FAO/WHO Expert Committee on Food Additives and published by FAO. It is a different document from any above, written by a different body and revised on its own cycle; it is advisory, and a country adopts it or does not.
Cyclohexane
Synonyms: Hexahydrobenzene
Assay, identification and purity criteria
Description and assay
- Specification history
- Prepared at the 23rd JECFA (1979), published in FNP 12 (1979) and in FNP 52 (1992). Metals and arsenic specifications revised at the 63rd JECFA (2004). No ADI was allocated at the 23rd JECFA (1979)
- DEFINITION Chemical names C.A.S. number Chemical formula
- Cyclohexane 110-82-7 C 6 H 12
- Formula weight Assay
- 84.16 Not less than 99.5% w/w
- DESCRIPTION FUNCTIONAL USES
- Colourless, clear, flammable liquid, with characteristic odour Extraction solvent
- METHOD OF ASSAY
- Proceed as directed under the Gas-liquid chromatographic method for Determination of Aromatic Hydrocarbons (see Volume 4) and calculate the content by the method of area percentage (area normalization).
Identification
- Solubility (Vol. 4) Specific gravity (Vol. 4) Distillation range (Vol. 4)
- Insoluble in water; miscible with ethanol and ether 0.776 - 0.780 80 o - 82 o
Purity criteria
- Non-volatile residue (Vol. 4) Sulphur (Vol. 4) Benzene (Vol. 4)
- Not more than 1 mg/100 ml Not more than 10 mg/kg Not more than 0.1% v/v Determine by the method Aromatic Hydrocarbon Determination
- Polycyclic aromatic hydrocarbons (Vol. 4)
- The following absorbance limits per cm of optical path length shall not be exceeded: wavelength (nm) absorbance 280 - 289 0.15 290 - 299 0.12 300 - 359 0.08 360 - 400 0.02
- Lead (Vol. 4)
- Not more than 2 mg/kg Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, “Instrumental Methods.”
Every name it appears under
60 recorded names. A label may use any of them.
CAS registry number
- 110-82-7
- 12217-02-6
Other names
- 48K5MKG32S
- Acid red 300
- ASTM Method D5191 Vapor Pressure - 22.5 kPa (3.26 psi)
- Benzene hexahydride
- Benzene, hexahydro-
- Benzenehexahydride
- CAS-110-82-7
- Caswell No. 269
- CCRIS 3928
- Cicloesano
- Ciclohexano
- cyclo-hexane
- Cyclohexaan
- Cyclohexan
- Cyclohexane
- Cyclohexane 2000 microg/mL in Methanol
- Cyclohexane packed in clear glass ampule
- Cyclohexane Solution in Methanol, 1000ug/mL
- Cyclohexane Solution in Methanol, 100ug/mL
- Cyclohexane, ACS Grade
- Cyclohexane, ACS reagent, >=99%
- Cyclohexane, ACS spectrophotometric grade, >=99%
- Cyclohexane, analytical standard
- Cyclohexane, anhydrous, 99.5%
- Cyclohexane, AR, >=99.5%
- Cyclohexane, for HPLC
- Cyclohexane, for HPLC, >=99.7%
- Cyclohexane, for HPLC, >=99.9%
- Cyclohexane, HPLC Grade
- Cyclohexane, HPLC grade, >=99.9%
- Cyclohexane, HPLC UV/IR isocratic grade, min. 99.9%
- Cyclohexane, JIS special grade
- Cyclohexane, Laboratory Reagent, >=99.8%
- Cyclohexane, LR, >=99%
- Cyclohexane, p.a., 99.0%
- Cyclohexane, p.a., ACS reagent, 99.0%
- Cyclohexane, Pharmaceutical Secondary Standard; Certified Reference Material
- Cyclohexane, puriss. p.a., ACS reagent, >=99.5% (GC)
- Cyclohexane, puriss., >=99.5% (GC)
- Cyclohexane, SAJ first grade, >=99.0%
- Cyclohexane, UV HPLC spectroscopic, 99.5%
- CYCLOHEXANE- D12
- Cykloheksan
- cylcohexane
- cylohexane
- EPA Pesticide Chemical Code 025901
- ghl.PD_Mitscher_leg0.242
- hexahydro-Benzene
- Hexahydrobenzene
- Hexamethylene
- Hexanaphthene
- HSDB 60
- InChI=1/C6H12/c1-2-4-6-5-3-1/h1-6H
- Phthalate ester quality control substance in polyvinyl chloride
- RCRA waste no. U056
- RCRA waste number U056
- WLN: L6TJ
- Zyklohexan
Hazard reference values
No reference value for this substance in the sources we hold.
Evidence and how bodies read it
Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.
Common questions
Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.
- What is Cyclohexane?
- Cyclohexane is a colourless flammable liquid used as an extraction solvent. Like the other solvents JECFA specifies, it is meant to be removed from the food it was used on, and the specification governs its purity rather than a level in food.
- What is Cyclohexane used for in food?
- It is listed as a solvent — the role the US assigns it. This page shows every function each regulator records, with the citation for each.
- Is Cyclohexane vegan?
- Yes. Cyclohexane is not derived from animals, and is suitable for vegetarians. This page says what it is made from and how.
Sources for this page
- jecfaspecs retrieved 2026-09-23
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