Disodium 5'-ribonucleotides — Food Additive Index

Where it is and isn’t permitted

Status of Disodium 5'-ribonucleotides by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
Jurisdiction	Status	Scope and limits	Citation
United StatesFood and Drug Administration	Not listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.
Codex AlimentariusCodex Alimentarius Commission / JECFA	Permitted, with conditions	9 food categories no numerical limit (good manufacturing practice) Show every food category 04.2.2.7 Fermented vegetable (including mushrooms and fungi, roots and tubers, pulses and legumes, and aloe vera) and seaweed products, excluding fermented soybean products of food categories 06.8.6, 06.8.7, 12.9.1, — GMP 06.4.2 Dried pastas and noodles and like products — GMP 09.2.1 Frozen fish, fish fillets, and fish products, including molluscs, crustaceans, and echinoderms — GMP 09.2.2 Frozen battered fish, fish fillets and fish products, including molluscs, crustaceans, and echinoderms — GMP 09.2.3 Frozen minced and creamed fish products, including molluscs, crustaceans, and echinoderms — GMP 09.2.4 Cooked and/or fried fish and fish products, including molluscs, crustaceans, and echinoderms — GMP 09.2.5 Smoked, dried, fermented, and/or salted fish and fish products, including molluscs, crustaceans, and echinoderms — GMP 12.1.2 Salt substitutes — GMP 14.1.5 Coffee, coffee substitutes, tea, herbal infusions, and other hot cereal and grain beverages, excluding cocoa — GMP	CXS 192-1995 Table Three, INS 635and 9 further provisionsretrieved 2026-09-07

What it is made from

A mixture of the two ribonucleotides, both normally produced by fermentation but also obtainable from animal sources.

Vegan status depends on the source
Vegetarian status depends on the source
May raise a halal question
May raise a kosher question

This is not an omission. What this additive is made from is not fixed — depending on the manufacturer it may be plant, animal or microbial in origin, nobody is required to say which, and the same product can change source between production runs. Ask the manufacturer if it matters to you; a label cannot answer it.

Every name it appears under

5 recorded names. A label may use any of them.

E number

E635

INS number

Other names

DISODIUM 5'-RIBONUCLEOTIDES
E 635
Sodium 5'-ribonucleotide

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated by hand rather than machine-read, and none has been written for this substance yet.

Sources for this page

gsfa retrieved 2026-09-07

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable:/api/v1/additives/disodium-5-ribonucleotides.json