Iron-choline citrate complex

CAS 1336-80-7

Listed as a nutrient supplement by the US.

Listed as nutrient supplements (US)
Chemical structure of Iron-choline citrate complex, from PubChem compound 46174080
Structure from PubChem CID 46174080 (National Library of Medicine, public domain). A depiction of one compound: where a listing covers a family, or a substance has no single structure, this page shows none.

Iron-choline citrate is an iron source for foods for special dietary use, supplying iron and choline together.

Where it is and isn’t permitted

Status of Iron-choline citrate complex by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
Australia and New ZealandFood Standards Australia New ZealandNo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.
CanadaHealth CanadaNo listing matchedHealth Canada’s lists name additives without E or INS numbers, so this site matches them by exact name. A substance listed there under a name this site does not recognise has no row here.
European UnionEuropean Commission / EFSANo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.
Great BritainFood Standards Agency / Food Standards ScotlandNo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.
JapanConsumer Affairs AgencyNo listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance.
South KoreaMinistry of Food and Drug SafetyNo listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance.
United StatesFood and Drug AdministrationPermitted, with conditions21 CFR 172.370retrieved 2026-10-17
Codex AlimentariusCodex Alimentarius Commission / JECFANot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.

How much is permitted

A listing usually limits the quantity as well as the food. Only one of the forms that takes is a figure: quantum satis and good manufacturing practice permit the amount the technological effect requires and no more, which is a limit rather than the absence of one. Figures below are the range across every food category this page is listed in, and categories differ between regulators — see how much is permitted.

United States—1 no quantity stated

No regulator sets a figure for Iron-choline citrate complex. That is not an absence of control: where the listing says quantum satis or good manufacturing practice, the quantity is limited to what the effect requires.

What it is made from

Made by complexing an iron salt with choline and citric acid.

  • Vegan
  • Vegetarian

Compare other additives on the dietary indexes.

CAS registry number
1336-80-7
InChIKey
UQSASSBWRKBREL-UHFFFAOYSA-K
PubChem
CID 46174080

Every name it appears under

26 recorded names. A label may use any of them.

CAS registry number

  • 1336-80-7

As it appears in regulation

  • Iron-choline citrate complex

Other names

  • (HYDROGEN CITRATO(3-))TRIAQUOIRON, CHOLINE SALT
  • Chelate prepared by reacting equimolar quantities of freshly precipitated ferric hydroxide with choline dihydrogen citrate
  • FERRIC CHOLINE CITRATE
  • Ferricholinatum
  • Ferrocholinate (INN)
  • FERROCHOLINATE (MART.)
  • Ferrocholinate [INN]
  • Ferrocholinate citrate
  • ferrocholinate trihydrate
  • Ferrocholinatum
  • Ferrocholinatum (INN-Latin)
  • Ferrocolinato
  • Ferrocolinato (INN-Spanish)
  • FERROLIP
  • Fre-Sol
  • Fre-Sol (TN)
  • Iron choline citrate
  • LWI5ZJ8WVL

Systematic names

  • 2-Hydroxy-N,N,N-trimethylethanaminium triaqua(2-hydroxy-1,2,3-tricarboxylatoferrate, (OC-6-44)
  • ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, (OC-6-44)-TRIAQUA(2-(HYDROXY-.KAPPA.O)-1,2,3-PROPANETRICARBOXYLATO(4-)-.KAPPA.O1,.KAPPA.O2)FERRATE(1-) (1:1)
  • ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, (OC-6-44)-TRIAQUA(2-(HYDROXY-KAPPAO)-1,2,3-PROPANETRICARBOXYLATO(4-)-KAPPAO1,KAPPAO2)FERRATE(1-) (1:1)
  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (OC-6-44)-triaqua(2-hydroxy-1,2,3-propanetricarboxylato(4-))ferrate(1-)
  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxy(2-hydroxy-1,2,3-propanetricarboxylato(4-))ferrate(1-)
  • Ferrate(1-), triaqua(2-hydroxy-1,2,3-propanetricarboxylato(4-))-, (oc-6-44)-, 2-hydroxy-N,N,N-trimethylethanaminium

Hazard reference values

No reference value for this substance in the sources we hold.

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.

Common questions

Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.

What is Iron-choline citrate complex?
Iron-choline citrate is an iron source for foods for special dietary use, supplying iron and choline together.
What is Iron-choline citrate complex used for in food?
It is listed as a nutrient supplement — the role the US assigns it. This page shows every function each regulator records, with the citation for each.
Is Iron-choline citrate complex banned in Europe?
No. Iron-choline citrate complex is not on the EU's list of authorised food additives, but it would not be expected to be: every role regulators give it — nutrient supplement — the EU regulates under separate law. Its absence from the additives list says nothing about whether it is permitted in Europe.
Where is Iron-choline citrate complex permitted?
Of the seven regulators this site reads, the US permits it. Each permission is for named foods at named levels, not a blanket one; the table on this page gives them with citations.
Is Iron-choline citrate complex vegan?
Yes. Iron-choline citrate complex is not derived from animals, and is suitable for vegetarians. This page says what it is made from and how.

Sources for this page

  • ecfr retrieved 2026-10-17

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable: a JSON record of this additive is given on request —how to ask for access.

Follow changes to Iron-choline citrate complex:Atom feed — regulatory events, and any change the weekly refresh detects in its provisions.