Potassium polyaspartate

E number E456INS 456CAS 64723-18-8

Listed as a stabiliser by Codex.

Listed as stabilisers (Codex)

Potassium polyaspartate is a wine stabiliser that prevents tartrate crystals by interfering with how they grow, an alternative to cold stabilisation, in which the wine is chilled for days.

Where it is and isn’t permitted

Status of Potassium polyaspartate by jurisdiction. Every jurisdiction this site covers is listed, including those where the substance does not appear.
JurisdictionStatusScope and limitsCitation
Australia and New ZealandFood Standards Australia New ZealandPermitted, with conditions

1 food category

highest permitted level 100 mg/kg

Food Standards Code, Schedule 15, S15—5, item 14.2.2, INS 456retrieved 2026-10-17
CanadaHealth CanadaPermitted, with conditions

highest permitted level 100 mg/kg

In: Fruit wine; Wine. Purpose: To inhibit crystal formation. Limit: 100 ppm. Amendment notices: NOM/ADM-0162.

Health Canada, List of Permitted Food Additives with Other Purposes of Use (List 8), item P.11retrieved 2026-10-17
European UnionEuropean Commission / EFSANo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.
Great BritainFood Standards Agency / Food Standards ScotlandNo listed food uses foundThis site has not matched this substance to any food use on this jurisdiction’s list of authorised food additives. A food additive may be used only in foods that list names. Flavourings, enzymes, processing aids and added nutrients are regulated separately and do not appear on it.
JapanConsumer Affairs AgencyNo listing matchedThis site imports only Japan’s list of designated additives (Appended Table 1 to the Regulations for Enforcement of the Food Sanitation Act), matched by English name. Existing additives, natural flavouring agents and ordinary foods used as additives are permitted outside that list and are not imported, so an empty row does not show that Japan does not permit the substance.
South KoreaMinistry of Food and Drug SafetyNo listing matchedThis site imports Part III of South Korea’s Standards and Specifications for Food Additives, matched by CAS number, then INS number, then exact name. Mixed preparations and sanitisers are not imported, and an entry whose identifiers disagreed with a page’s is held for review, so an empty row does not show that South Korea does not permit the substance.
United StatesFood and Drug AdministrationNot listedDoes not appear on this jurisdiction’s permitted list. That is not the same as being prohibited.
Codex AlimentariusCodex Alimentarius Commission / JECFAPermitted, with conditions

1 food category

highest permitted level 100 mg/kg

CXS 192-1995 Table One, INS 456, food category 14.2.3retrieved 2026-09-07

How much is permitted

A listing usually limits the quantity as well as the food. Only one of the forms that takes is a figure: quantum satis and good manufacturing practice permit the amount the technological effect requires and no more, which is a limit rather than the absence of one. Figures below are the range across every food category this page is listed in, and categories differ between regulators — see how much is permitted.

Australia and New Zealand100 mg/kg1 numeric limit
Canada100 mg/kg1 numeric limit
Codex Alimentarius100 mg/kg1 numeric limit

GRAS notices to the FDA

A GRAS notice is a company’s conclusion that a substance is generally recognised as safe for the use it describes. FDA’s letter responds to that conclusion, for that notifier and that use. It is not a listing in 21 CFR, and it is not counted as a US permission above. The substance and use are as FDA’s inventory words them; this site matched the notice to this page by exact name.

  • GRN No. 770 · Potassium polyaspartate · Enartis USA, Inc.

    Intended use: Intended for use as a stabilizer in wine at levels up to 300 mg/L.

    FDA’s response (2018-09-11): FDA has no questions

What it is made from

Produced by polymerising aspartic acid and neutralising with potassium.

  • Vegan
  • Vegetarian

Compare other additives on the dietary indexes.

CAS registry number
64723-18-8

How the EU defines it

The legal specification an additive must meet to be sold as this E number in the EU — what it is, how it may be made, and the purity it must reach. From Commission Regulation (EU) No 231/2012.

A specification does not authorise use. This site holds no EU permission for Potassium polyaspartate in food; see the EU row in the status panel above.

E 456 Potassium polyaspartate

Potassium polyaspartate is the potassium salt of polyaspartic acid, produced from L-aspartic acid and potassium hydroxide. The thermic process transforms the aspartic acid in polysuccinimide that is insoluble. Polysuccinimide is treated with potassium hydroxide allowing the opening of the ring and polymerisation of the units. The last step is the spray drying phase, which results in a light tan powder

Assay, identification and purity criteria

Description and assay

CAS number
64723-18-8
Chemical name
L-aspartic acid, homopolymer, potassium salt
Chemical formula
[C₄H₄NO₃K]ₙ
Weight average molecular weight
Approximately 5 300 g/mol
Assay
Not less than 98 % on dry weight basis
Particle size
Not less than 45 μm (not more than 1 % in weight of particles of less than 45 μm)
Description
A light brown odourless powder

Identification

Solubility
Very soluble in water and slightly soluble in organic solvents
pH
7,5-8,5 (40 % aqueous solution)

Purity criteria

Degree of substitutions
Not less than 91,5 % on dry weight basis
Loss on drying
Not more than 11 % (105 °C,12 hours)
Potassium hydroxide
Not more than 2 %
Aspartic acid
Not more than 1 %
Other impurities
Not more than 0,1 %
Arsenic
Not more than 2,5 mg/kg
Lead
Not more than 1,5 mg/kg
Mercury
Not more than 0,5 mg/kg
Cadmium
Not more than 0,1 mg/kg

Commission Regulation (EU) No 231/2012, Annex, E 456

Every name it appears under

27 recorded names. A label may use any of them.

E number

  • E456

INS number

  • 456

CAS registry number

  • 64723-18-8

As it appears in regulation

  • Potassium Polyaspartate

Other names

  • E 456
  • POTASSIUM POLYASPARTATE

Systematic names

  • Dipotassium;(2S)-2-aminobutanedioate

Hazard reference values

Values set by assessing bodies. A body that has not set a value is not listed here.
TypeValuePopulationAssessed byOpinion
ADInot specified—JECFA2019

Evidence and how bodies read it

Studies, and the differing conclusions regulators drew from them, are curated rather than machine-read, and none has been written for this substance yet.

Common questions

Assembled from what is above, in the words the questions are usually asked in. Each answer is the same statement the relevant section makes, with the same citations behind it.

What is E 456?
E 456 is Potassium polyaspartate. Potassium polyaspartate is a wine stabiliser that prevents tartrate crystals by interfering with how they grow, an alternative to cold stabilisation, in which the wine is chilled for days.
What is Potassium polyaspartate used for in food?
It is listed as a stabiliser — the role Codex assigns it. This page shows every function each regulator records, with the citation for each.
Where is Potassium polyaspartate permitted?
Of the seven regulators this site reads, Australia and New Zealand, Canada and the Codex standard permit it. Each permission is for named foods at named levels, not a blanket one; the table on this page gives them with citations.
Is Potassium polyaspartate vegan?
Yes. Potassium polyaspartate is not derived from animals, and is suitable for vegetarians. This page says what it is made from and how.

Sources for this page

  • anz retrieved 2026-10-17
  • ca retrieved 2026-10-17
  • gsfa retrieved 2026-09-07
  • euspecs retrieved 2026-10-18

Full licence terms and publisher details on Sources. How this page is built and updated: Method.

Machine-readable: a JSON record of this additive is given on request —how to ask for access.

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